1
/
of
1
NSJ Bioreagents
SKU:F50788-0.08ML
ALK1 Antibody / ACVRL1
ALK1 Antibody / ACVRL1
Regular price
$205.00 USD
Regular price
Sale price
$205.00 USD
Unit price
/
per
Shipping calculated at checkout.
Couldn't load pickup availability
ACVRL1 is a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. This protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2.
Specifications
| Family | Primary antibody |
|---|---|
| Formulation | In 1X PBS, pH 7.4, with 0.09% sodium azide |
| Format | Purified |
| Host Animal | Rabbit |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit Ig |
| Species Reactivity | Human, Mouse |
| Application | WB, FACS, IHC, ELISA |
| Application Details | Flow Cytometry: 1:10-1:50,IHC (Paraffin): 1:50-1:100,Western blot: 1:1000 |
| Application Note | Titration of the ALK1 antibody may be required due to differences in protocols and secondary/substrate sensitivity. |
| Immunogen | A portion of amino acids 38-68 from the human protein was used as the immunogen for this ALK1 antibody. |
| Purity | Purified |
| Storage | Aliquot the ALK1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles. |
| Limitation | This ALK1 antibody is available for research use only. |
| Uniprot # | P37023 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/alk1-antibody-acvrl1-f50788 |
| Title | ALK1 Antibody / ACVRL1 |
| Description | ACVRL1 is a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. This protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2. |
Share
