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NSJ Bioreagents

SKU:RQ7034

Aldehyde dehydrogenase 3 Antibody / ALDH3A1

Aldehyde dehydrogenase 3 Antibody / ALDH3A1

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ALDH3A1 (Aldehyde Dehydrogenase, Family 3, Subfamily A, Member 1), also known as ALDH3, is an enzyme that in humans is encoded by the ALDH3A1 gene. By in situ hybridization, Hiraoka et al.(1995) mapped the ALDH3 gene to 17p11.2. ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. This protein preferentially oxidizes aromatic aldehyde substrates. It may play a role in the oxidation of toxic aldehydes.

Specifications

Family Primary antibody
Formulation 0.5mg/ml if reconstituted with 0.2ml sterile DI water
Format Antigen affinity purified
Host Animal Rabbit
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Species Reactivity Human
Application WB, IHC-P, IF, Direct ELISA
Application Details Western blot: 0.5-1 ug/ml,Immunohistochemistry (FFPE): 2-5ug/ml,Immunofluorescence: 5ug/ml,Direct ELISA: 0.1-0.5ug/ml
Application Note Optimal dilution of the Aldehyde dehydrogenase 3 antibody should be determined by the researcher.
Localization Cytoplasmic
Immunogen Recombinant human protein (amino acids Y413-H453) was used as the immunogen for the Aldehyde dehydrogenase 3 antibody.
Buffer Lyophilized from 1X PBS with 2% Trehalose
Purity Antigen affinity purified
Storage After reconstitution, the Aldehyde dehydrogenase 3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitation This Aldehyde dehydrogenase 3 antibody is available for research use only.
Uniprot # P30838
Status Available
PDF Link https://www.nsjbio.com/tds-pdf/aldehyde-dehydrogenase-3-antibody-aldh3a1-rq7034
Title Aldehyde dehydrogenase 3 Antibody / ALDH3A1
Description ALDH3A1 (Aldehyde Dehydrogenase, Family 3, Subfamily A, Member 1), also known as ALDH3, is an enzyme that in humans is encoded by the ALDH3A1 gene. By in situ hybridization, Hiraoka et al.(1995) mapped the ALDH3 gene to 17p11.2. ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. This protein preferentially oxidizes aromatic aldehyde substrates. It may play a role in the oxidation of toxic aldehydes.
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