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NSJ Bioreagents
SKU:RQ6930
ALAS2 Antibody / ASB / 5-aminolevulinic acid synthase 2
ALAS2 Antibody / ASB / 5-aminolevulinic acid synthase 2
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Delta-aminolevulinate synthase 2 also known as ALAS2 is a protein that in humans is encoded by the ALAS2 gene. The product of this gene specifies an erythroid-specific mitochondrially located enzyme. The encoded protein catalyzes the first step in the heme biosynthetic pathway. Defects in this gene cause X-linked pyridoxine-responsive sideroblastic anemia. Alternatively spliced transcript variants encoding different isoforms have been identified.
Specifications
| Family | Primary antibody |
|---|---|
| Formulation | 0.5mg/ml if reconstituted with 0.2ml sterile DI water |
| Format | Antigen affinity purified |
| Host Animal | Rabbit |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit IgG |
| Species Reactivity | Human, Mouse, Rat |
| Application | WB, FACS, IF, Direct ELISA |
| Application Details | Western blot: 0.5-1 ug/ml,Flow cytometry: 1-3ug/million cells,Immunofluorescence: 5ug/ml,Direct ELISA: 0.1-0.5ug/ml |
| Application Note | Optimal dilution of the ALAS2 antibody should be determined by the researcher. |
| Immunogen | Recombinant human protein (amino acids M1-D190) was used as the immunogen for the ALAS2 antibody. |
| Buffer | Lyophilized from 1X PBS with 2% Trehalose |
| Purity | Antigen affinity purified |
| Storage | After reconstitution, the ALAS2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing. |
| Limitation | This ALAS2 antibody is available for research use only. |
| Uniprot # | P22557 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/alas2-antibody-asb-5-aminolevulinic-acid-synthase-2-rq6930 |
| Title | ALAS2 Antibody / ASB / 5-aminolevulinic acid synthase 2 |
| Description | Delta-aminolevulinate synthase 2 also known as ALAS2 is a protein that in humans is encoded by the ALAS2 gene. The product of this gene specifies an erythroid-specific mitochondrially located enzyme. The encoded protein catalyzes the first step in the heme biosynthetic pathway. Defects in this gene cause X-linked pyridoxine-responsive sideroblastic anemia. Alternatively spliced transcript variants encoding different isoforms have been identified. |
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