1
/
of
1
NSJ Bioreagents
SKU:RQ5401
ALAS1 Antibody / 5'-Aminolevulinate synthase 1
ALAS1 Antibody / 5'-Aminolevulinate synthase 1
Regular price
$449.00 USD
Regular price
Sale price
$449.00 USD
Unit price
/
per
Shipping calculated at checkout.
Couldn't load pickup availability
The ALAS1 gene encodes the mitochondrial enzyme which is catalyzes the rate-limiting step in heme (iron-protoporphyrin) biosynthesis. The enzyme encoded by this gene is the housekeeping enzyme; a separate gene encodes a form of the enzyme that is specific for erythroid tissue. The level of the mature encoded protein is regulated by heme: high levels of heme down-regulate the mature enzyme in mitochondria while low heme levels up-regulate.
Specifications
| Family | Primary antibody |
|---|---|
| Formulation | Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA |
| Format | Purified |
| Clone | EOA-1 |
| Host Animal | Rabbit |
| Clonality | Rabbit Monoclonal |
| Isotype | Rabbit IgG |
| Species Reactivity | Human |
| Application | IF/ICC, WB |
| Application Details | Western blot: 1:500-1:2000,Immunofluorescence/Immunocytochemistry: 1:50-1:200 |
| Application Note | Optimal dilution of the ALAS1 antibody should be determined by the researcher. |
| Immunogen | A synthetic peptide specific to human ALAS1 was used as the immunogen for the ALAS1 antibody. |
| Purity | Affinity purified |
| Storage | Store the ALAS1 antibody at -20oC. |
| Limitation | This ALAS1 antibody is available for research use only. |
| Uniprot # | P13196 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/alas1-antibody-rq5401 |
| Title | ALAS1 Antibody / 5'-Aminolevulinate synthase 1 |
| Description | The ALAS1 gene encodes the mitochondrial enzyme which is catalyzes the rate-limiting step in heme (iron-protoporphyrin) biosynthesis. The enzyme encoded by this gene is the housekeeping enzyme; a separate gene encodes a form of the enzyme that is specific for erythroid tissue. The level of the mature encoded protein is regulated by heme: high levels of heme down-regulate the mature enzyme in mitochondria while low heme levels up-regulate. |
Share
