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NSJ Bioreagents
SKU:RQ8698
AKAP8 Antibody / A-kinase anchor protein 8 / AKAP 95
AKAP8 Antibody / A-kinase anchor protein 8 / AKAP 95
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AKAP8 is an anchoring protein that mediates the subcellular compartmentation of cAMP-dependent protein kinase. Acts as an anchor for a PKA-signaling complex onto mitotic chromosomes, which is required for maintenance of chromosomes in a condensed form throughout mitosis. Recruits condensin complex subunit NCAPD2 to chromosomes required for chromatin condensation; the function appears to be independent from PKA-anchoring. [UniProt]
Specifications
| Family | Primary antibody |
|---|---|
| Formulation | Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA |
| Format | Purified |
| Clone | 29A07 |
| Host Animal | Rabbit |
| Clonality | Recombinant Rabbit Monoclonal |
| Isotype | Rabbit IgG |
| Species Reactivity | Human |
| Application | WB |
| Application Details | Western blot: 1:500-1:2000 |
| Application Note | Optimal dilution of the AKAP8 antibody should be determined by the researcher. |
| Immunogen | A synthetic peptide specific to human A-kinase anchor protein 8 was used as the immunogen for the AKAP8 antibody. |
| Purity | Affinity chromatography |
| Storage | Store the AKAP8 antibody at -20oC. |
| Limitation | This AKAP8 antibody is available for research use only. |
| Uniprot # | O43823 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/akap8-antibody-a-kinase-anchor-protein-8-akap-95-29a07-rq8698 |
| Title | AKAP8 Antibody / A-kinase anchor protein 8 / AKAP 95 |
| Description | AKAP8 is an anchoring protein that mediates the subcellular compartmentation of cAMP-dependent protein kinase. Acts as an anchor for a PKA-signaling complex onto mitotic chromosomes, which is required for maintenance of chromosomes in a condensed form throughout mitosis. Recruits condensin complex subunit NCAPD2 to chromosomes required for chromatin condensation; the function appears to be independent from PKA-anchoring. [UniProt] |
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