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NSJ Bioreagents
SKU:F53944-0.05ML
AKAP13 Antibody
AKAP13 Antibody
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A-kinase anchor protein 13 anchors cAMP-dependent protein kinase (PKA) and acts as an adapter protein to selectively couple G alpha-13 and Rho. Augments gene activation by the estrogen receptor in an element- specific and ligand-dependent manner. Activates estrogen receptor beta by a p38 MAPK-dependent pathway. Stimulates exchange activity on Rho proteins in vitro, but not on CDC42, Ras or Rac and may bind calcium ions.
Specifications
| Family | Primary antibody |
|---|---|
| Formulation | In 1X PBS, pH 7.4, with 0.09% sodium azide |
| Format | Purified |
| Clone | 1742CT411.87.24 |
| Host Animal | Mouse |
| Clonality | Monoclonal (mouse origin) |
| Isotype | Mouse IgG1, kappa |
| Species Reactivity | Human |
| Application | WB |
| Application Details | Western blot: 1:4000-8000 |
| Application Note | Titration of the AKAP13 antibody may be required due to differences in protocols and secondary/substrate sensitivity. |
| Immunogen | A partial recombinant protein corresponding to amino acids 18-170 from the human protein was used as the immunogen for the AKAP13 antibody. |
| Purity | Protein G affinity chromatography |
| Storage | Aliquot the AKAP13 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles. |
| Limitation | This AKAP13 antibody is available for research use only. |
| Uniprot # | Q12802 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/akap13-antibody-1742ct4118724-f53944 |
| Title | AKAP13 Antibody |
| Description | A-kinase anchor protein 13 anchors cAMP-dependent protein kinase (PKA) and acts as an adapter protein to selectively couple G alpha-13 and Rho. Augments gene activation by the estrogen receptor in an element- specific and ligand-dependent manner. Activates estrogen receptor beta by a p38 MAPK-dependent pathway. Stimulates exchange activity on Rho proteins in vitro, but not on CDC42, Ras or Rac and may bind calcium ions. |
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