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NSJ Bioreagents
SKU:RQ4816
AIFM1 Antibody / AIF / Apoptosis-Inducing Factor
AIFM1 Antibody / AIF / Apoptosis-Inducing Factor
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'Apoptosis-inducing factor 1, mitochondrial' functions both as NADH oxidoreductase and as regulator of apoptosis. In response to apoptotic stimuli, it is released from the mitochondrion intermembrane space into the cytosol and to the nucleus, where it functions as a proapoptotic factor in a caspase-independent pathway. In contrast, functions as an antiapoptotic factor in normal mitochondria via its NADH oxidoreductase activity.
Specifications
| Family | Primary antibody |
|---|---|
| Formulation | Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA |
| Format | Purified |
| Clone | GH-1 |
| Host Animal | Rabbit |
| Clonality | Rabbit Monoclonal |
| Isotype | Rabbit IgG |
| Species Reactivity | Human |
| Application | WB |
| Application Details | Western blot: 1:500-1:2000 |
| Application Note | Optimal dilution of the AIFM1 antibody should be determined by the researcher. |
| Immunogen | A synthetic peptide specific to human AIF / AIFM1 was used as the immunogen for the AIFM1 antibody. |
| Purity | Affinity purified |
| Storage | Store the AIFM1 antibody at -20oC. |
| Limitation | This AIFM1 antibody is available for research use only. |
| Uniprot # | O95831 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/aifm1-antibody-aif-apoptosis-inducing-factor-gh-1-rq4816 |
| Title | AIFM1 Antibody / AIF / Apoptosis-Inducing Factor |
| Description | 'Apoptosis-inducing factor 1, mitochondrial' functions both as NADH oxidoreductase and as regulator of apoptosis. In response to apoptotic stimuli, it is released from the mitochondrion intermembrane space into the cytosol and to the nucleus, where it functions as a proapoptotic factor in a caspase-independent pathway. In contrast, functions as an antiapoptotic factor in normal mitochondria via its NADH oxidoreductase activity. |
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