NSJ Bioreagents
SKU:RQ8894
AIF-1 Antibody / Allograft inflammatory factor 1 / IBA1
AIF-1 Antibody / Allograft inflammatory factor 1 / IBA1
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Allograft inflammatory factor 1 (AIF-1) is a cytoplasmic, calcium-binding protein predominantly expressed in activated macrophages and microglia. It is involved in the regulation of immune and inflammatory responses, contributing to cell proliferation, migration, and cytokine production. AIF-1 plays roles in vascular pathology, tissue repair, and immune-mediated diseases. <p>Elevated expression of AIF-1 has been associated with various pathological conditions, including atherosclerosis, autoimmune disorders, and neuroinflammation. It serves as a marker for activated immune cells, making it valuable for studying inflammation-related mechanisms and disease progression. <p>Using a high-quality AIF-1 antibody allows sensitive detection in applications such as western blot, immunohistochemistry, and immunofluorescence. An AIF-1 antibody from NSJ Bioreagents provides reliable performance for research in immunology, neurobiology, and cardiovascular disease. Selecting the right AIF-1 antibody ensures accurate and reproducible experimental outcomes.
Specifications
| Family | Primary antibody |
|---|---|
| Formulation | Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA |
| Format | Purified |
| Clone | AFGH-1 |
| Host Animal | Rabbit |
| Clonality | Recombinant Rabbit Monoclonal |
| Isotype | Rabbit IgG |
| Species Reactivity | Human |
| Application | WB, IHC-P |
| Application Details | Western blot: 1:500,Immunohistochemistry (FFPE): 1:50 |
| Application Note | Optimal dilution of the AIF-1 antibody should be determined by the researcher. |
| Localization | Cytoplasm |
| Immunogen | A peptide sequence specific to Allograft inflammatory factor 1 was used as the immunogen for the AIF-1 antibody. |
| Purity | Affinity chromatography |
| Storage | After reconstitution, the AIF-1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing. |
| Limitation | This AIF-1 antibody is available for research use only. |
| Uniprot # | P55008 |
| Status | Available |
| PDF Link | http://www.nsjbio.com/tds-pdf/aif-1-antibody-allograft-inflammatory-factor-1-iba1-rq8894 |
| Title | AIF-1 Antibody / Allograft inflammatory factor 1 / IBA1 |
| Description | Allograft inflammatory factor 1 (AIF-1) is a cytoplasmic, calcium-binding protein predominantly expressed in activated macrophages and microglia. It is involved in the regulation of immune and inflammatory responses, contributing to cell proliferation, migration, and cytokine production. AIF-1 plays roles in vascular pathology, tissue repair, and immune-mediated diseases. <p>Elevated expression of AIF-1 has been associated with various pathological conditions, including atherosclerosis, autoimmune disorders, and neuroinflammation. It serves as a marker for activated immune cells, making it valuable for studying inflammation-related mechanisms and disease progression. <p>Using a high-quality AIF-1 antibody allows sensitive detection in applications such as western blot, immunohistochemistry, and immunofluorescence. An AIF-1 antibody from NSJ Bioreagents provides reliable performance for research in immunology, neurobiology, and cardiovascular disease. Selecting the right AIF-1 antibody ensures accurate and reproducible experimental outcomes. |
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