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NSJ Bioreagents
SKU:R32620
AFF4 Antibody / AF4/FMR2 family member 4
AFF4 Antibody / AF4/FMR2 family member 4
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$449.00 USD
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The AFF4 gene encodes a scaffold protein that functions as a core component of the super elongation complex (SEC), which is involved in transcriptional regulation during embryogenesis. The protein encoded by this gene belongs to the AF4 family of transcription factors involved in leukemia. It is a component of the positive transcription elongation factor b (P-TEFb) complex. This gene is mapped to chromosome 5q31.
Specifications
| Family | Primary antibody |
|---|---|
| Formulation | 0.5mg/ml if reconstituted with 0.2ml sterile DI water |
| Format | Antigen affinity purified |
| Host Animal | Rabbit |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit IgG |
| Species Reactivity | Human |
| Application | WB, IHC-P, FACS, IP |
| Application Details | Western blot: 0.5-1ug/ml,Immunohistochemistry (FFPE): 2-5ug/ml,Flow cytometry: 1-3ug/million cells,Immunoprecipitation: 2ug per 500ug of lysate |
| Application Note | Optimal dilution of the AFF4 antibody should be determined by the researcher. |
| Immunogen | Amino acids 6-53 (RNVLRMKERERRNQEIQQGEDAFPPSSPLFAEPYKVTSKEDKLSSRIQ-human) were used as the immunogen for the AFF4 antibody. |
| Buffer | Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide |
| Purity | Antigen affinity |
| Storage | After reconstitution, the AFF4 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing. |
| Limitation | This AFF4 antibody is available for research use only. |
| Uniprot # | Q9UHB7 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/aff4-antibody-af4fmr2-family-member-4-r32620 |
| Title | AFF4 Antibody / AF4/FMR2 family member 4 |
| Description | The AFF4 gene encodes a scaffold protein that functions as a core component of the super elongation complex (SEC), which is involved in transcriptional regulation during embryogenesis. The protein encoded by this gene belongs to the AF4 family of transcription factors involved in leukemia. It is a component of the positive transcription elongation factor b (P-TEFb) complex. This gene is mapped to chromosome 5q31. |
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