NSJ Bioreagents
SKU:R31906
ADRB2 Antibody
ADRB2 Antibody
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ADRB2, also known as beta-2 adrenergic receptor, is a beta-adrenergic receptor within a cell membrane which reacts with adrenaline (epinephrine) as a hormone or neurotransmitter affecting muscles or organs. It is mapped to 5q32. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. The genetic variation in the ADRB2 gene may be of major importance for obesity, energy expenditure, and lipolytic ADRB2 function in adipose tissue, at least in women. What�s more, it has been found that activation of ADRB2 receptors can stimulate gamma-secretase activity and beta-amyloid production, and the ADRB2 receptors activator may contribute to beta-amyloid accumulation in AD.
Specifications
| Family | Primary antibody |
|---|---|
| Formulation | 0.5mg/ml if reconstituted with 0.2ml sterile DI water |
| Format | Antigen affinity purified |
| Host Animal | Rabbit |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit IgG |
| Species Reactivity | Human, Rat |
| Application | WB |
| Application Details | Western blot: 0.1-0.5ug/ml |
| Application Note | Optimal dilution of the ADRB2 antibody should be determined by the researcher. |
| Immunogen | Amino acids RVFQEAKRQLQKIDKSEGRFHVQNLSQVEQDGRTGH of human ADRB2 were used as the immunogen for the ADRB2 antibody. |
| Buffer | Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide |
| Purity | Antigen affinity |
| Storage | After reconstitution, the ADRB2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing. |
| Limitation | This ADRB2 antibody is available for research use only. |
| Uniprot # | P07550 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/adrb2-antibody-r31906 |
| Title | ADRB2 Antibody |
| Description | ADRB2, also known as beta-2 adrenergic receptor, is a beta-adrenergic receptor within a cell membrane which reacts with adrenaline (epinephrine) as a hormone or neurotransmitter affecting muscles or organs. It is mapped to 5q32. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. The genetic variation in the ADRB2 gene may be of major importance for obesity, energy expenditure, and lipolytic ADRB2 function in adipose tissue, at least in women. What�s more, it has been found that activation of ADRB2 receptors can stimulate gamma-secretase activity and beta-amyloid production, and the ADRB2 receptors activator may contribute to beta-amyloid accumulation in AD. |
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