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NSJ Bioreagents

SKU:F54417-0.08ML

ADH1C Antibody / Alcohol dehydrogenase 1C

ADH1C Antibody / Alcohol dehydrogenase 1C

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This gene encodes class I alcohol dehydrogenase, gamma subunit, which is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. Class I alcohol dehydrogenase, consisting of several homo- and heterodimers of alpha, beta, and gamma subunits, exhibits high activity for ethanol oxidation and plays a major role in ethanol catabolism. Three genes encoding alpha, beta and gamma subunits are tandemly organized in a genomic segment as a gene cluster.

Specifications

Family Primary antibody
Formulation In 1X PBS, pH 7.4, with 0.09% sodium azide
Format Purified
Host Animal Rabbit
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Species Reactivity Human
Application FACS, IF, IHC-P, WB
Application Details Flow cytometry: 1:25 (1x10e6 cells),Immunofluorescence: 1:25,Immunohistochemistry (FFPE): 1:25,Western blot: 1:500-1:2000
Application Note The stated application concentrations are suggested starting points. Titration of the ADH1C antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Localization Cytoplasmic
Immunogen A portion of amino acids 231-260 from the human protein was used as the immunogen for the ADH1C antibody.
Purity Antigen affinity purified
Storage Aliquot the ADH1C antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitation This ADH1C antibody is available for research use only.
Uniprot # P00326
Status Available
PDF Link https://www.nsjbio.com/tds-pdf/adh1c-antibody-alcohol-dehydrogenase-1c-f54417
Title ADH1C Antibody / Alcohol dehydrogenase 1C
Description This gene encodes class I alcohol dehydrogenase, gamma subunit, which is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. Class I alcohol dehydrogenase, consisting of several homo- and heterodimers of alpha, beta, and gamma subunits, exhibits high activity for ethanol oxidation and plays a major role in ethanol catabolism. Three genes encoding alpha, beta and gamma subunits are tandemly organized in a genomic segment as a gene cluster.
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