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NSJ Bioreagents

SKU:RQ7318

ADAR2 Antibody / ADARB1 / RED1

ADAR2 Antibody / ADARB1 / RED1

Regular price $449.00 USD
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Double-stranded RNA-specific editase 1 is an enzyme that in humans is encoded by the ADARB1 gene. This gene encodes the enzyme responsible for pre-mRNA editing of the glutamate receptor subunit B by site-specific deamination of adenosines. Studies in rat found that this enzyme acted on its own pre-mRNA molecules to convert an AA dinucleotide to an AI dinucleotide which resulted in a new splice site. Alternative splicing of this gene results in several transcript variants, some of which have been characterized by the presence or absence of an ALU cassette insert and a short or long C-terminal region.

Specifications

Family Primary antibody
Formulation 0.5mg/ml if reconstituted with 0.2ml sterile DI water
Format Antigen affinity purified
Host Animal Rabbit
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Species Reactivity Human, Mouse, Rat
Application WB, FACS, Direct ELISA
Application Details Western blot: 0.5-1ug/ml, Flow cytometry: 1-3ug/million cells, Direct ELISA: 0.1-0.5ug/ml
Application Note Optimal dilution of the ADAR2 antibody should be determined by the researcher.
Immunogen Recombinant human protein (amino acids K234-R714) was used as the immunogen for the ADAR2 antibody.
Buffer Lyophilized from 1X PBS with 2% Trehalose
Purity Antigen affinity purified
Storage After reconstitution, the ADAR2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitation This ADAR2 antibody is available for research use only.
Uniprot # P78563
Status Available
PDF Link https://www.nsjbio.com/tds-pdf/adar2-antibody-adarb1-red1-rq7318
Title ADAR2 Antibody / ADARB1 / RED1
Description Double-stranded RNA-specific editase 1 is an enzyme that in humans is encoded by the ADARB1 gene. This gene encodes the enzyme responsible for pre-mRNA editing of the glutamate receptor subunit B by site-specific deamination of adenosines. Studies in rat found that this enzyme acted on its own pre-mRNA molecules to convert an AA dinucleotide to an AI dinucleotide which resulted in a new splice site. Alternative splicing of this gene results in several transcript variants, some of which have been characterized by the presence or absence of an ALU cassette insert and a short or long C-terminal region.
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