NSJ Bioreagents
SKU:RQ8804
ADAM2 Antibody / Disintegrin and metalloproteinase domain-containing protein 2
ADAM2 Antibody / Disintegrin and metalloproteinase domain-containing protein 2
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Disintegrin and metalloproteinase domain-containing protein 2 or Beta-fertilin is an enzyme that in humans is encoded by the ADAM2 gene. This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The encoded protein is a subunit of an integral sperm membrane glycoprotein called fertilin, which plays an important role in sperm-egg interactions. Alternative splicing results in multiple transcript variants encoding different isoforms.
Specifications
| Family | Primary antibody |
|---|---|
| Formulation | 0.5mg/ml if reconstituted with 0.2ml sterile DI water |
| Format | Antigen affinity purified |
| Host Animal | Rabbit |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit IgG |
| Species Reactivity | Human |
| Application | WB, FACS, ELISA |
| Application Details | Western blot: 1-2ug/ml,Flow cytometry: 1-3ug/million cells,ELISA: 0.1-0.5ug/ml |
| Application Note | Optimal dilution of the ADAM2 antibody should be determined by the researcher. |
| Immunogen | An E.coli-derived human recombinant protein (amino acids L228-Y277) was used as the immunogen for the ADAM2 antibody. |
| Buffer | Lyophilized from 1X PBS with 2% Trehalose |
| Purity | Antigen affinity chromatography |
| Storage | After reconstitution, the ADAM2 Antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing. |
| Limitation | This ADAM2 antibody is available for research use only. |
| Uniprot # | Q99965 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/adam2-antibody-disintegrin-and-metalloproteinase-domain-containing-protein-2-rq8804 |
| Title | ADAM2 Antibody / Disintegrin and metalloproteinase domain-containing protein 2 |
| Description | Disintegrin and metalloproteinase domain-containing protein 2 or Beta-fertilin is an enzyme that in humans is encoded by the ADAM2 gene. This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The encoded protein is a subunit of an integral sperm membrane glycoprotein called fertilin, which plays an important role in sperm-egg interactions. Alternative splicing results in multiple transcript variants encoding different isoforms. |
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