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NSJ Bioreagents
SKU:RQ7326
ACSS2 Antibody / Acetyl-coenzyme A synthetase
ACSS2 Antibody / Acetyl-coenzyme A synthetase
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Acyl-coenzyme A synthetase short-chain family member 2 is an enzyme that in humans is encoded by the ACSS2 gene. This gene encodes a cytosolic enzyme that catalyzes the activation of acetate for use in lipid synthesis and energy generation. The protein acts as a monomer and produces acetyl-CoA from acetate in a reaction that requires ATP. Expression of this gene is regulated by sterol regulatory element-binding proteins, transcription factors that activate genes required for the synthesis of cholesterol and unsaturated fatty acids. Alternative splicing results in multiple transcript variants.
Specifications
| Family | Primary antibody |
|---|---|
| Formulation | 0.5mg/ml if reconstituted with 0.2ml sterile DI water |
| Format | Antigen affinity purified |
| Host Animal | Rabbit |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit IgG |
| Species Reactivity | Human, Mouse, Rat |
| Application | WB, FACS, IHC-P, Direct ELISA |
| Application Details | Western blot: 0.5-1ug/ml, Flow cytometry: 1-3ug/million cells, Direct ELISA: 0.1-0.5ug/ml,Immunohistochemistry (FFPE): 2-5ug/ml |
| Application Note | Optimal dilution of the ACSS2 antibody should be determined by the researcher. |
| Localization | Cytoplasmic, nuclear |
| Immunogen | Recombinant human protein (amino acids E201-A651) was used as the immunogen for the ACSS2 antibody. |
| Buffer | Lyophilized from 1X PBS with 2% Trehalose |
| Purity | Antigen affinity purified |
| Storage | After reconstitution, the ACSS2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing. |
| Limitation | This ACSS2 antibody is available for research use only. |
| Uniprot # | Q9NR19 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/acss2-antibody-acetyl-coenzyme-a-synthetase-rq7326 |
| Title | ACSS2 Antibody / Acetyl-coenzyme A synthetase |
| Description | Acyl-coenzyme A synthetase short-chain family member 2 is an enzyme that in humans is encoded by the ACSS2 gene. This gene encodes a cytosolic enzyme that catalyzes the activation of acetate for use in lipid synthesis and energy generation. The protein acts as a monomer and produces acetyl-CoA from acetate in a reaction that requires ATP. Expression of this gene is regulated by sterol regulatory element-binding proteins, transcription factors that activate genes required for the synthesis of cholesterol and unsaturated fatty acids. Alternative splicing results in multiple transcript variants. |
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