• Western blot testing of human 1) HeLa and 2) Jurkat cell lysate with ACO2 antibody at 1:1000. Predicted molecular weight ~85 kDa.
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NSJ Bioreagents

F50512-0.08ML

ACO2 Antibody / Aconitase 2

ACO2 Antibody / Aconitase 2

$205.00 USD
$205.00 USD
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Aconitase 2 belongs to the aconitase/IPM isomerase family. It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle. It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15(PRSS15), also known as Lon protease, after oxidative modification.

Specifications

Family Primary antibody
Formulation In 1X PBS, pH 7.4, with 0.09% sodium azide
Format Purified
Host Animal Rabbit
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Species Reactivity Human
Application WB, IHC, ELISA
Application Details Western blot: 1:500-1000,IHC (Paraffin): 1:10-1:50
Application Note Titration of the ACO2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Localization Cytoplasmic, granular
Immunogen A portion of amino acids 294-325 from the human protein was used as the immunogen for this ACO2 antibody.
Purity Purified
Storage Aliquot the ACO2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitation This ACO2 antibody is available for research use only.
Uniprot # Q99798
Status Available
PDF Link https://www.nsjbio.com/tds-pdf/aco2-antibody-aconitase-2-f50512
Title ACO2 Antibody / Aconitase 2
Description Aconitase 2 belongs to the aconitase/IPM isomerase family. It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle. It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15(PRSS15), also known as Lon protease, after oxidative modification.
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