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NSJ Bioreagents

SKU:N1078-25UG

Acid Phosphatase Antibody (Isoform 2 specific)

Acid Phosphatase Antibody (Isoform 2 specific)

Regular price $225.00 USD
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Acid phosphatases are a broad family of enzymes that differ widely in their amino acid length and homology, molecular weight and tissue of origin. They function to remove phosphate groups (or dephosphorylate) from proteins and perform best under acidic conditions. Disease states are sometimes characterized by abnormally high or low levels of Acid Phosphatase, leading to them being used as serological and histological disease markers. Prostatic Acid Phosphatase (PAP) was initially used as a prostate cancer marker but was later replaced with Prostate Serum Antigen (PSA), a more sensitive early stage cancer marker.

Specifications

Family Primary antibody
Formulation 0.5 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Format Purified
Host Animal Rabbit
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Species Reactivity Human
Application WB
Application Details Western blot: 1-3ug/ml
Application Note <p>Provided assay concentrations are suggestions only, Acid Phosphatase antibody titration may be required for optimal results. </p><p>1. This antibody is specific to isoforms 2 (or B) and E of Acid Phosphatase.</p>
Immunogen The amino acid sequence used as immunogen for this antibody is specific to isoforms 2 (or B) and E of Acid Phosphatase.
Buffer 1X PBS, pH 7.4
Purity Protein A affinity chromatography
Storage Aliquot the Acid Phosphatase antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitation This Acid Phosphatase antibody is available for research use only.
Status Available
PDF Link https://www.nsjbio.com/tds-pdf/acid-phosphatase-antibody-isoform-2-specific-n1078
Title Acid Phosphatase Antibody (Isoform 2 specific)
Description Acid phosphatases are a broad family of enzymes that differ widely in their amino acid length and homology, molecular weight and tissue of origin. They function to remove phosphate groups (or dephosphorylate) from proteins and perform best under acidic conditions. Disease states are sometimes characterized by abnormally high or low levels of Acid Phosphatase, leading to them being used as serological and histological disease markers. Prostatic Acid Phosphatase (PAP) was initially used as a prostate cancer marker but was later replaced with Prostate Serum Antigen (PSA), a more sensitive early stage cancer marker.
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