NSJ Bioreagents
SKU:F50830-0.08ML
Acetylcholinesterase Antibody / ACHE
Acetylcholinesterase Antibody / ACHE
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Acetylcholinesterase hydrolyzes the neurotransmitter, acetylcholine at neuromuscular junctions and brain cholinergic synapses, and thus terminates signal transmission. The Protein is also found on the red blood cell membranes, where it constitutes the Yt blood group antigen. Acetylcholinesterase exists in multiple molecular forms which possess similar catalytic properties, but differ in their oligomeric assembly and mode of cell attachment to the cell surface. The major form of acetylcholinesterase found in brain, muscle and other tissues is the hydrophilic species, which forms disulfide-linked oligomers with collagenous, or lipid-containing structural subunits.
Specifications
| Family | Primary antibody |
|---|---|
| Formulation | In 1X PBS, pH 7.4, with 0.09% sodium azide |
| Format | Purified |
| Host Animal | Rabbit |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit Ig |
| Species Reactivity | Human |
| Predicted Species Reactivity | Guinea pig |
| Application | IHC-P, FACS, IF, WB, ELISA |
| Application Details | Western blot: 1:1000,Immunohistochemistry (FFPE): 1:10-1:50,Flow cytometry: 1:10-1:50,Immunofluorescence: 1:10-1:50 |
| Application Note | Titration of the Acetylcholinesterase antibody may be required due to differences in protocols and secondary/substrate sensitivity. |
| Localization | Cytoplasmic, membranous |
| Immunogen | A portion of amino acids 147-175 from the human protein was used as the immunogen for this Acetylcholinesterase antibody. |
| Purity | Purified |
| Storage | Aliquot the Acetylcholinesterase antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles. |
| Limitation | This Acetylcholinesterase antibody is available for research use only. |
| Uniprot # | P22303 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/acetylcholinesterase-antibody-ache-f50830 |
| Title | Acetylcholinesterase Antibody / ACHE |
| Description | Acetylcholinesterase hydrolyzes the neurotransmitter, acetylcholine at neuromuscular junctions and brain cholinergic synapses, and thus terminates signal transmission. The Protein is also found on the red blood cell membranes, where it constitutes the Yt blood group antigen. Acetylcholinesterase exists in multiple molecular forms which possess similar catalytic properties, but differ in their oligomeric assembly and mode of cell attachment to the cell surface. The major form of acetylcholinesterase found in brain, muscle and other tissues is the hydrophilic species, which forms disulfide-linked oligomers with collagenous, or lipid-containing structural subunits. |
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