• Western blot testing of human 1) HEK293, 2) Raji, 3) A549, 4) Caco-2, 5) T-47D, 6) rat spleen, 7) rat lung and 8) mouse lung tissue lysate with ABIN-1 antibody. Expected molecular weight: 72-85 kDa.
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NSJ Bioreagents

RQ6402

ABIN-1 Antibody / TNIP1

ABIN-1 Antibody / TNIP1

$449.00 USD
$449.00 USD
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TNFAIP3-interacting protein 1, also called ABIN-1 or A20-binding inhibitor of NF-kappa-B activation 1, is a protein that in humans is encoded by the TNIP1 gene. This gene encodes an A20-binding protein which plays a role in autoimmunity and tissue homeostasis through the regulation of nuclear factor kappa-B activation. Mutations in this gene have been associated with psoriatic arthritis, rheumatoid arthritis, and systemic lupus erythematosus. Multiple transcript variants encoding different isoforms have been found for this gene.

Specifications

Family Primary antibody
Formulation 0.5mg/ml if reconstituted with 0.2ml sterile DI water
Format Purified
Host Animal Rabbit
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Species Reactivity Human, Mouse, Rat
Application WB, Direct ELISA
Application Details Western blot: 0.5-1ug/ml,Direct ELISA: 0.1-0.5ug/ml
Application Note Optimal dilution of the ABIN-1 antibody should be determined by the researcher.
Localization Cytoplasmic, nuclear
Immunogen Recombinant human protein (amino acids E312-K371) was used as the immunogen for the ABIN-1 antibody.
Buffer Lyophilized from 1X PBS with 2% Trehalose
Purity Antigen affinity purified
Storage After reconstitution, the ABIN-1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitation This ABIN-1 antibody is available for research use only.
Uniprot # Q15025
Status Available
PDF Link https://www.nsjbio.com/tds-pdf/abin-1-antibody-tnip1-rq6402
Title ABIN-1 Antibody / TNIP1
Description TNFAIP3-interacting protein 1, also called ABIN-1 or A20-binding inhibitor of NF-kappa-B activation 1, is a protein that in humans is encoded by the TNIP1 gene. This gene encodes an A20-binding protein which plays a role in autoimmunity and tissue homeostasis through the regulation of nuclear factor kappa-B activation. Mutations in this gene have been associated with psoriatic arthritis, rheumatoid arthritis, and systemic lupus erythematosus. Multiple transcript variants encoding different isoforms have been found for this gene.
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