NSJ Bioreagents
SKU:F40498-0.08ML
ABCC3 Antibody
ABCC3 Antibody
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Canalicular multispecific organic anion transporter 2 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in the transport of biliary and intestinal excretion of organic anions. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.
Specifications
| Family | Primary antibody |
|---|---|
| Formulation | In 1X PBS, pH 7.4, with 0.09% sodium azide |
| Format | Antigen affinity purified |
| Host Animal | Rabbit |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit Ig |
| Species Reactivity | Human |
| Application | IHC, FACS, WB, ELISA |
| Application Details | Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Flow Cytometry: 1:10-1:50 |
| Application Note | Titration of the ABCC3 antibody may be required due to differences in protocols and secondary/substrate sensitivity. |
| Localization | Cytoplasmic, membranous |
| Immunogen | A portion of amino acids 899-925 from the human protein was used as the immunogen for this ABCC3 antibody. |
| Purity | Antigen affinity |
| Storage | Aliquot the ABCC3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles. |
| Limitation | This ABCC3 antibody is available for research use only. |
| Uniprot # | O15438 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/abcc3-antibody-f40498 |
| Title | ABCC3 Antibody |
| Description | Canalicular multispecific organic anion transporter 2 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in the transport of biliary and intestinal excretion of organic anions. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. |
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