NSJ Bioreagents
SKU:F48871-0.08ML
ABCC11 Antibody
ABCC11 Antibody
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ATP-binding cassette sub-family C member 11 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This ABC full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. The product of this gene participates in physiological processes involving bile acids, conjugated steroids, and cyclic nucleotides. In addition, a SNP in this gene is responsible for determination of human earwax type. This gene and family member ABCC12 are determined to be derived by duplication and are both localized to chromosome 16q12.1.
Specifications
| Family | Primary antibody |
|---|---|
| Formulation | In 1X PBS, pH 7.4, with 0.09% sodium azide |
| Format | Antigen affinity purified |
| Host Animal | Rabbit |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit Ig |
| Species Reactivity | Human |
| Application | WB, IHC, ELISA |
| Application Details | Western blot: 1:1000,IHC (Paraffin): 1:50-1:100 |
| Application Note | Titration of the ABCC11 antibody may be required due to differences in protocols and secondary/substrate sensitivity. |
| Localization | Cytoplasmic, membranous |
| Immunogen | A portion of amino acids 343-372 from the human protein was used as the immunogen for this ABCC11 antibody. |
| Purity | Antigen affinity |
| Storage | Aliquot the ABCC11 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles. |
| Limitation | This ABCC11 antibody is available for research use only. |
| Uniprot # | Q96J66 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/abcc11-antibody-f48871 |
| Title | ABCC11 Antibody |
| Description | ATP-binding cassette sub-family C member 11 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This ABC full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. The product of this gene participates in physiological processes involving bile acids, conjugated steroids, and cyclic nucleotides. In addition, a SNP in this gene is responsible for determination of human earwax type. This gene and family member ABCC12 are determined to be derived by duplication and are both localized to chromosome 16q12.1. |
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