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NSJ Bioreagents
SKU:R31688
ABCB4 Antibody / MDR3
ABCB4 Antibody / MDR3
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Adenosine triphosphate-binding cassette subfamily B, member 4, also called MDR3, is a protein that in humans is encoded by the ABCB4 gene. The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABCB4 mutations represent a genetic factor involved in this peculiar form of cholesterol gallstone disease in adults.
Specifications
| Family | Primary antibody |
|---|---|
| Formulation | 0.5mg/ml if reconstituted with 0.2ml sterile DI water |
| Format | Antigen affinity purified |
| Host Animal | Rabbit |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit IgG |
| Species Reactivity | Human, Mouse, Rat |
| Application | FACS, IHC-P, WB |
| Application Details | Immunohistochemistry (FFPE): 2-5ug/ml,FACS: 1-3ug/million cells,Western blot: 0.5-1ug/ml |
| Application Note | Variations in secondary/substrate sensitivities and test protocols may require the ABCB4 antibody to be titrated for optimal performance. |
| Localization | Cell membrane, cytoplasm |
| Immunogen | Human partial recombinant protein (AA 601-720) was used as the immunogen for this ABCB4 antibody. |
| Buffer | Lyophilized from 1X PBS with 2% Trehalose |
| Purity | Antigen affinity |
| Storage | The lyophilized ABCB4 antibody can be stored at 4oC to -20oC. After reconstitution, aliquot and store at -20oC. Avoid repeated freeze/thaws. |
| Limitation | This ABCB4 antibody is available for research use only. |
| Uniprot # | P21439 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/abcb4-antibody-mdr3-r31688 |
| Title | ABCB4 Antibody / MDR3 |
| Description | Adenosine triphosphate-binding cassette subfamily B, member 4, also called MDR3, is a protein that in humans is encoded by the ABCB4 gene. The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABCB4 mutations represent a genetic factor involved in this peculiar form of cholesterol gallstone disease in adults. |
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