NSJ Bioreagents
SKU:R36498-100UG
ABCA4 Antibody / ATP-binding cassette sub-family A member 4
ABCA4 Antibody / ATP-binding cassette sub-family A member 4
Couldn't load pickup availability
The ABCA4 protein is a transporter molecule responsible for moving retinal molecules across cell membranes in the eye and may have a broader impact on neurological processes. Research has shown that this protein is not restricted to the eyes, but is also present in various regions of the brain. ABCA4 plays a role in the maintenance of lipid homeostasis in the central nervous system. Lipids are essential components of cell membranes and are crucial for neuronal function. Disruptions in lipid metabolism have been implicated in numerous neurological disorders, including Alzheimer's disease and Parkinson's disease. ABCA4 has been found to interact with other proteins involved in synaptic transmission and neuronal signaling. This suggests that the protein may play a role in modulating communication between neurons, which is essential for cognitive function.
Specifications
| Family | Primary antibody |
|---|---|
| Formulation | 0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide |
| Format | Antigen affinity purified |
| Host Animal | Goat |
| Clonality | Polyclonal (goat origin) |
| Isotype | Goat Ig |
| Species Reactivity | Human, Mouse |
| Application | IF, ELISA (peptide) |
| Application Details | Immunofluorescence: 10ug/ml,ELISA (peptide) LOD: 1:128000 |
| Application Note | Optimal dilution of the ABCA4 antibody should be determined by the researcher. |
| Localization | Membrane, ER, Cytoplasmic vesicles |
| Immunogen | Amino acids KQQTESHDLPLHPR were used as the immunogen for this ABCA4 antibody. |
| Purity | Antigen affinity |
| Storage | Aliquot and store the ABCA4 antibody at -20oC. |
| Limitation | This ABCA4 antibody is available for research use only. |
| Uniprot # | P16284 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/abca4-antibody-atp-binding-cassette-sub-family-a-member-4-r36498 |
| Title | ABCA4 Antibody / ATP-binding cassette sub-family A member 4 |
| Description | The ABCA4 protein is a transporter molecule responsible for moving retinal molecules across cell membranes in the eye and may have a broader impact on neurological processes. Research has shown that this protein is not restricted to the eyes, but is also present in various regions of the brain. ABCA4 plays a role in the maintenance of lipid homeostasis in the central nervous system. Lipids are essential components of cell membranes and are crucial for neuronal function. Disruptions in lipid metabolism have been implicated in numerous neurological disorders, including Alzheimer's disease and Parkinson's disease. ABCA4 has been found to interact with other proteins involved in synaptic transmission and neuronal signaling. This suggests that the protein may play a role in modulating communication between neurons, which is essential for cognitive function. |
Share
