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NSJ Bioreagents
SKU:F54418-0.08ML
AADC Antibody / DOPA Decarboxylase / DDC
AADC Antibody / DOPA Decarboxylase / DDC
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$205.00 USD
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This protein catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine. Defects in this gene are the cause of aromatic L-amino-acid decarboxylase deficiency (AADCD). AADCD deficiency is an inborn error in neurotransmitter metabolism that leads to combined serotonin and catecholamine deficiency.
Specifications
| Family | Primary antibody |
|---|---|
| Formulation | In 1X PBS, pH 7.4, with 0.09% sodium azide |
| Format | Purified |
| Host Animal | Rabbit |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit Ig |
| Species Reactivity | Human, Mouse |
| Application | FACS, IHC-P, WB, IF |
| Application Details | Flow cytometry: 1:25 (1x10e6 cells),Immunohistochemistry (FFPE): 1:25,Western blot: 1:500-1:2000,Immunofluorescence: 1:25 |
| Application Note | The stated application concentrations are suggested starting points. Titration of the AADCantibody may be required due to differences in protocols and secondary/substrate sensitivity. |
| Localization | Cytoplasmic |
| Immunogen | A portion of amino acids 32-61 from the human protein was used as the immunogen for the AADC antibody. |
| Purity | Antigen affinity purified |
| Storage | Aliquot the AADC antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles. |
| Limitation | This AADC antibody is available for research use only. |
| Uniprot # | P20711 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/aadc-antibody-dopa-decarboxylase-ddc-f54418 |
| Title | AADC Antibody / DOPA Decarboxylase / DDC |
| Description | This protein catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine. Defects in this gene are the cause of aromatic L-amino-acid decarboxylase deficiency (AADCD). AADCD deficiency is an inborn error in neurotransmitter metabolism that leads to combined serotonin and catecholamine deficiency. |
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