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NSJ Bioreagents
SKU:RQ8505
4-Alpha-glucanotransferase Antibody / AGL / Glycogen debranching enzyme
4-Alpha-glucanotransferase Antibody / AGL / Glycogen debranching enzyme
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This gene encodes the glycogen debrancher enzyme which is involved in glycogen degradation. This enzyme has two independent catalytic activities which occur at different sites on the protein: a 4-alpha-glucotransferase activity and a amylo-1,6-glucosidase activity. Mutations in this gene are associated with glycogen storage disease although a wide range of enzymatic and clinical variability occurs which may be due to tissue-specific alternative splicing. Alternatively spliced transcripts encoding different isoforms have been described.
Specifications
| Family | Primary antibody |
|---|---|
| Formulation | 0.5mg/ml if reconstituted with 0.2ml sterile DI water |
| Format | Antigen affinity purified |
| Host Animal | Rabbit |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit IgG |
| Species Reactivity | Human, Mouse, Rat |
| Application | WB, IHC-P, IF, FACS, ELISA |
| Application Details | Western blot: 0.5-1ug/ml,Immunohistochemistry (FFPE): 2-5ug/ml,Immunofluorescence: 5ug/ml,Flow cytometry: 1-3ug/million cells,ELISA: 0.1-0.5ug/ml |
| Application Note | Optimal dilution of the 4-Alpha-glucanotransferase antibody should be determined by the researcher. |
| Immunogen | An E.coli-derived human recombinant protein (amino acids H3-K265) was used as the immunogen for the 4-Alpha-glucanotransferase antibody. |
| Buffer | Lyophilized from 1X PBS with 2% Trehalose |
| Purity | Antigen affinity purified |
| Storage | After reconstitution, the 4-Alpha-glucanotransferase antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing. |
| Limitation | This 4-Alpha-glucanotransferase antibody is available for research use only. |
| Uniprot # | P35573 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/4-alpha-glucanotransferase-antibody-agl-glycogen-debranching-enzyme-rq8505 |
| Title | 4-Alpha-glucanotransferase Antibody / AGL / Glycogen debranching enzyme |
| Description | This gene encodes the glycogen debrancher enzyme which is involved in glycogen degradation. This enzyme has two independent catalytic activities which occur at different sites on the protein: a 4-alpha-glucotransferase activity and a amylo-1,6-glucosidase activity. Mutations in this gene are associated with glycogen storage disease although a wide range of enzymatic and clinical variability occurs which may be due to tissue-specific alternative splicing. Alternatively spliced transcripts encoding different isoforms have been described. |
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