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NSJ Bioreagents
SKU:RQ7344
17-beta-HSD 3 Antibody / HSD17B3
17-beta-HSD 3 Antibody / HSD17B3
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17beta-Hydroxysteroid dehydrogenase 3 (17b-HSD3) is an enzyme that in humans is encoded by the HSD17B3 gene and is involved in androgen steroidogenesis. This isoform of 17 beta-hydroxysteroid dehydrogenase is expressed predominantly in the testis and catalyzes the conversion of androstenedione to testosterone. It preferentially uses NADP as cofactor. Deficiency can result in male pseudohermaphroditism with gynecomastia.
Specifications
| Family | Primary antibody |
|---|---|
| Formulation | 0.5mg/ml if reconstituted with 0.2ml sterile DI water |
| Format | Antigen affinity purified |
| Host Animal | Rabbit |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit IgG |
| Species Reactivity | Human, Mouse, Rat |
| Application | WB, FACS |
| Application Details | Western blot: 0.5-1ug/ml,Flow cytometry: 1-3ug/million cells |
| Application Note | Optimal dilution of the 17-beta-HSD 3 antibody should be determined by the researcher. |
| Immunogen | Amino acids NLLPSHFLNAPDEIQSLIH were used as the immunogen for the 17-beta-HSD 3 antibody. |
| Buffer | Lyophilized from 1X PBS with 2% Trehalose |
| Purity | Antigen affinity purified |
| Storage | After reconstitution, the 17-beta-HSD 3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing. |
| Limitation | This 17-beta-HSD 3 antibody is available for research use only. |
| Uniprot # | P37058 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/17-beta-hsd-3-antibody-hsd17b3-rq7344 |
| Title | 17-beta-HSD 3 Antibody / HSD17B3 |
| Description | 17beta-Hydroxysteroid dehydrogenase 3 (17b-HSD3) is an enzyme that in humans is encoded by the HSD17B3 gene and is involved in androgen steroidogenesis. This isoform of 17 beta-hydroxysteroid dehydrogenase is expressed predominantly in the testis and catalyzes the conversion of androstenedione to testosterone. It preferentially uses NADP as cofactor. Deficiency can result in male pseudohermaphroditism with gynecomastia. |
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