NR2E3 Antibody

Size

100ug

Clone Number

Aliases

ESCS antibody; MGC49976 antibody; NR2 E3 antibody; Nr2e3 antibody; NR2E3_HUMAN antibody; Nuclear receptor subfamily 2 group E member 3 antibody; Photoreceptor specific nuclear receptor antibody; Photoreceptor-specific nuclear receptor antibody; PNR antibody; Rd 7 antibody; Rd7 antibody; Retina specific nuclear receptor antibody; Retina-specific nuclear receptor antibody; Retinal degeneration 7 antibody; RNR antibody; RP37 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9Y5X4

Immunogen

Recombinant Human Photoreceptor-specific nuclear receptor protein (112-222AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC; Recommended dilution: IHC:1:200-1:500

Background

Orphan nuclear receptor of retinal photoreceptor cells. Transcriptional factor that is an activator of rod development and repressor of cone development. Binds the promoter region of a number of rod- and cone-specific genes, including rhodopsin, M- and S-opsin and rod-specific phosphodiesterase beta subunit. Enhances rhodopsin expression. Represses M- and S-cone opsin expression.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

NR2E3

Research Areas

Neuroscience; Signal transduction