NR2E1 Antibody

Size

100ul

Clone Number

Aliases

hTll antibody; NR2E1 / Tailless antibody; nr2e1 antibody; NR2E1_HUMAN antibody; Nuclear receptor subfamily 2 group E member 1 antibody; Nuclear receptor TLX antibody; Orphan nuclear receptor NR2E1 antibody; Protein tailless homolog antibody; Tailless homolog antibody; Tll antibody; TLX antibody; XTLL antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9Y466

Immunogen

Recombinant Human Nuclear receptor subfamily 2 group E member 1 protein (106-385AA)

Raised in

Rabbit

Species Reactivity

Human, Mouse

Tested Applications

ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200

Background

Orphan receptor that binds DNA as a monomer to hormone response elements (HRE) containing an extended core motif half-site sequence 5\\\'-AAGGTCA-3\\\' in which the 5\\\' flanking nucleotides participate in determining receptor specificity (By similarity). May be required to pattern anterior brain differentiation. Involved in the regulation of retinal development and essential for vision. During retinogenesis, regulates PTEN-Cyclin D expression via binding to the promoter region of PTEN and suppressing its activity (By similarity). May be involved in retinoic acid receptor (RAR) regulation in retinal cells.

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

NR2E1

Research Areas

Epigenetics and Nuclear Signaling; Neuroscience; Signal transduction; Stem cells