NR1H2 Antibody

Size

100ug

Clone Number

Aliases

Liver X nuclear receptor beta antibody; Liver X receptor beta antibody; LX receptor beta antibody; LXR b antibody; LXR beta antibody; LXRB antibody; NER antibody; NER I antibody; NER1 antibody; NR1H 2 antibody; NR1H2 antibody; NR1H2_HUMAN antibody; Nuclear orphan receptor LXR beta antibody; Nuclear receptor NER antibody; Nuclear receptor subfamily 1 group H member 2 antibody; OR-1 antibody; Oxysterols receptor LXR-beta antibody; RIP15 antibody; Steroid hormone nuclear receptor NER antibody; Ubiquitously-expressed nuclear receptor antibody; UNR antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

P55055

Immunogen

Recombinant Human Oxysterols receptor LXR-beta protein (1-461AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200

Background

Nuclear receptor. Binds preferentially to double-stranded oligonucleotide direct repeats having the consensus half-site sequence 5\'-AGGTCA-3\' and 4-nt spacing (DR-4). Regulates cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR and LRP8; DLDLR and LRP8. Interplays functionally with RORA for the regulation of genes involved in liver metabolism (By similarity). Exhibits a ligand-dependent transcriptional activation activity (PubMed:25661920).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

NR1H2

Research Areas

Epigenetics and Nuclear Signaling; Cancer; Cardiovascular; Metabolism