NPY1-R Polyclonal Antibody

Ab type

Primary antibody

Background

NPY1R belongs to the G-protein-coupled receptor superfamily. The encoded transmembrane protein mediates the function of neuropeptide Y (NPY), a neurotransmitter, and peptide YY (PYY), a gastrointestinal hormone. The encoded receptor undergoes fast agonist-induced internalization through clathrin-coated pits and is subsequently recycled back to the cell membrane. Activation of Y1 receptors may result in mobilization of intracellular calcium and inhibition of adenylate cyclase activity.

Reactivity

Human;Mouse;Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human NPY1R. AA range:221-270

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

44392

synonyms

NPY1R; NPYR; NPYY1; Neuropeptide Y receptor type 1; NPY1-R