NOG Antibody

Size

100ug

Clone Number

Aliases

Nog antibody; NOGG_HUMAN antibody; Noggin antibody; SYM 1 antibody; SYM1 antibody; Symphalangism 1 (proximal) antibody; Synostoses (multiple) syndrome 1 antibody; SYNS 1 antibody; SYNS1 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q13253

Immunogen

Recombinant Human Noggin protein (28-232AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background

Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. Essential for cartilage morphogenesis and joint formation. Inhibits chondrocyte differentiation through its interaction with GDF5 and, probably, GDF6 (PubMed:21976273, PubMed:26643732).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

NOG

Research Areas

Developmental biology; Stem cells