NMNAT2 Antibody

Size

100ug

Clone Number

Aliases

C1orf15 antibody; KIAA0479 antibody; MGC2756 antibody; NaMN adenylyltransferase 2 antibody; Nicotinamide mononucleotide adenylyltransferase 2 antibody; Nicotinamide nucleotide adenylyltransferase 2 antibody; Nicotinate-nucleotide adenylyltransferase 2 antibody; NMN adenylyltransferase 2 antibody; NMNA2_HUMAN antibody; NMNAT 2 antibody; Nmnat2 antibody; PNAT 2 antibody; PNAT2 antibody; Pyridine nucleotide adenylyltransferase 2 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9BZQ4

Immunogen

Recombinant Human Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2 protein (1-153AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background

Catalyzes the formation of NAD(+) from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form; nicotinic acid mononucleotide (NaMN) as substrate but with a lower efficiency. Cannot use triazofurin monophosphate (TrMP) as substrate. Also catalyzes the reverse reaction, i.e. the pyrophosphorolytic cleavage of NAD(+). For the pyrophosphorolytic activity prefers NAD(+), NADH and NaAD as substrates and degrades nicotinic acid adenine dinucleotide phosphate (NHD) less effectively. Fails to cleave phosphorylated dinucleotides NADP(+), NADPH and NaADP(+).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

NMNAT2

Research Areas

Cancer; Metabolism; Signal transduction