NMBR Polyclonal Antibody

Ab type

Primary antibody

Background

This gene encodes a 7-transmembrane G protein-coupled receptor that binds neuromedin B, which is a growth factor and mitogen for gastrointestinal epithelial tissue and for normal and neoplastic lung. This receptor may play a role in smooth muscle contraction, neuronal responses, and the regulation of cell growth. Antagonists of this receptor have a potential therapeutic use in inhibiting tumor cell growth. Polymorphisms in this gene may be associated with a susceptibility for schizophrenia. Alternative splicing of this gene results in multiple transcript variants.

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthetic Peptide of NMBR

Storage Stability

-20°C for 1 year

Concentration

MolecularWeight_Da

synonyms

Neuromedin-B receptor; NMBR; Neuromedin-B receptor; NMB-R; Epididymis tissue protein Li 185a; Neuromedin-B-preferring bombesin receptor