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ABCbiolab

SKU:ABCCS53772

NLGN1 Antibody

NLGN1 Antibody

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Size

100ug

Clone Number

Aliases

NLG 1 antibody; KIAA1070 antibody; MGC45115 antibody; Neuroligin-1 antibody; NL1 antibody; NLG1 antibody; Nlgn1 antibody; NLGN1_HUMAN antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q8N2Q7

Immunogen

Recombinant Human Neuroligin-1 protein (51-300AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200

Background

Cell surface protein involved in cell-cell-interactions via its interactions with neurexin family members. Plays a role in synapse function and synaptic signal transmission, and probably mediates its effects by recruiting and clustering other synaptic proteins. May promote the initial formation of synapses, but is not essential for this. In vitro, triggers the de novo formation of presynaptic structures. May be involved in specification of excitatory synapses. Required to maintain wakefulness quality and normal synchrony of cerebral cortex activity during wakefulness and sleep.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

NLGN1

Research Areas

Neuroscience

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