ABCbiolab
SKU:ABCB06914
NIPA(Phospho Ser354) Polyclonal Antibody
NIPA(Phospho Ser354) Polyclonal Antibody
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Ab type
Primary antibody
Background
This gene encodes an F-box-containing protein that is a component of an SCF-type E3 ubiquitin ligase complex that regulates the onset of cell division. The G2/M transition in the cell cycle requires the interaction of the proteins cyclin B1 and cyclin-dependent kinase 1. The activated ubiquitin ligase complex targets the protein cyclin B1 for degradation| preventing this transition to mitosis.
Reactivity
Human, Mouse, Rat, Monkey
Clonality
Polyclonal
Host
Rabbit
Isotype
IgG
Immunogen
The antiserum was produced against synthesized peptide derived from human NIPA around the phosphorylation site of Ser354. AA range:320-369
Storage Stability
-20°C for 1 year
Concentration
1 mg/ml
MolecularWeight_Da
55262
synonyms
Nuclear-interacting partner of ALK; ZC3HC1; NIPA; HSPC216; Nuclear-interacting partner of ALK; Nuclear-interacting partner of anaplastic lymphoma kinase; hNIPA; Zinc finger C3HC-type protein 1
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