Nibrin(Phospho Ser343) Polyclonal Antibody

Ab type

Primary antibody

Background

Mutations in this gene are associated with Nijmegen breakage syndrome| an autosomal recessive chromosomal instability syndrome characterized by microcephaly| growth retardation| immunodeficiency| and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation.

Reactivity

Human, Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human p95/NBS1 around the phosphorylation site of Ser343. AA range:310-359

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

84959

synonyms

Nibrin; NBN; NBS; NBS1; P95; Nibrin; Cell cycle regulatory protein p95; Nijmegen breakage syndrome protein 1