NHERF-2 Polyclonal Antibody

Ab type

Primary antibody

Background

SLC9A3R2 (SLC9A3 regulator 2) encodes a member of the NHERF family of PDZ scaffolding proteins. These proteins mediate many cellular processes by binding to and regulating the membrane expression and protein-protein interactions of membrane receptors and transport proteins. The encoded protein plays a role in intestinal sodium absorption by regulating the activity of the sodium/hydrogen exchanger 3, and may also regulate the cystic fibrosis transmembrane regulator(CFTR) ion channel. Alternatively spliced transcript variants encoding multiple isoforms have been observed for SLC9A3R2.

Reactivity

Human;Mouse;Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from NHERF-2 . at AA range: 20-100

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

37414

synonyms

SLC9A3R2; NHERF2; Na(+)/H(+) exchange regulatory cofactor NHE-RF2; NHERF-2; NHE3 kinase A regulatory protein E3KARP; SRY-interacting protein 1; SIP-1; Sodium-hydrogen exchanger regulatory factor 2; So