NHEJ1 Antibody

Size

100ug

Clone Number

Aliases

Cernunnos antibody; FLJ12610 antibody; NHEJ 1 antibody; Nhej1 antibody; NHEJ1, S. cerevisiae, homolog of antibody; NHEJ1_HUMAN antibody; Non homologous end joining factor 1 antibody; Non-homologous end-joining factor 1 antibody; Nonhomologous end joining factor 1 antibody; OTTHUMP00000164168 antibody; OTTHUMP00000206275 antibody; OTTHUMP00000206279 antibody; Protein cernunnos antibody; XLF antibody; XRCC4 like factor antibody; XRCC4-like factor antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9H9Q4

Immunogen

Recombinant Human Non-homologous end-joining factor 1 protein (225-296AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IF; Recommended dilution: IF:1:50-1:200

Background

DNA repair protein involved in DNA nonhomologous end joining (NHEJ) required for double-strand break (DSB) repair and V(D)J recombination. May serve as a bridge between XRCC4 and the other NHEJ factors located at DNA ends, or may participate in reconfiguration of the end bound NHEJ factors to allow XRCC4 access to the DNA termini. It may act in concert with XRCC6/XRCC5 (Ku) to stimulate XRCC4-mediated joining of blunt ends and several types of mismatched ends that are noncomplementary or partially complementary (PubMed:16439204, PubMed:16439205, PubMed:17470781). Binds DNA in a length-dependent manner (PubMed:17317666).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

NHEJ1

Research Areas

Epigenetics and Nuclear Signaling