NFE2L2 Antibody

Size

100ul

Clone Number

2D12

Aliases

Nuclear factor erythroid 2-related factor 2 (NF-E2-related factor 2) (NFE2-related factor 2) (HEBP1) (Nuclear factor, erythroid derived 2, like 2), NFE2L2, NRF2

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q16236

Immunogen

A synthesized peptide derived from human Nrf2

Raised in

Species Reactivity

Human

Tested Applications

ELISA, IF; Recommended dilution: IF:1:20-1:200

Background

Transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes. Important for the coordinated up-regulation of genes in response to oxidative stress. May be involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the beta-globin locus control region.

Clonality

Monoclonal

Isotype

Rabbit IgG

Purification Method

Affinity-chromatography

Conjugate

Non-conjugated

Buffer

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

NFE2L2

Research Areas

Epigenetics and Nuclear Signaling; Cardiovascular; Cell biology; Metabolism