NFATC1 Antibody

Size

100ug

Clone Number

Aliases

cytoplasmic 1 antibody; MGC138448 antibody; NF ATc antibody; NF ATc1 antibody; NF-ATc antibody; NF-ATc1 antibody; NF-ATc1.2 antibody; NFAC1_HUMAN antibody; NFAT 2 antibody; NFAT transcription complex cytosolic component antibody; NFATC 1 antibody; NFATc antibody; NFATc1 antibody; Nuclear factor of activated T cells cytoplasmic 1 antibody; Nuclear factor of activated T cells cytoplasmic calcineurin dependent 1 antibody; Nuclear factor of activated T cells cytosolic component 1 antibody; nuclear factor of activated T-cells 'c' antibody; Nuclear factor of activated T-cells antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

O95644

Immunogen

Recombinant Human Nuclear factor of activated T-cells, cytoplasmic 1 protein (48-406AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC, IF; Recommended dilution: IHC:1:1000-1:2000, IF:1:50-1:200

Background

Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2 or IL-4 gene transcription. Also controls gene expression in embryonic cardiac cells. Could regulate not only the activation and proliferation but also the differentiation and programmed death of T-lymphocytes as well as lymphoid and non-lymphoid cells (PubMed:10358178). Required for osteoclastogenesis and regulates many genes important for osteoclast differentiation and function (By similarity).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

NFATC1

Research Areas

Epigenetics and Nuclear Signaling; Cardiovascular; Immunology; Signal transduction