NF-KappaB p65 Polyclonal Antibody

Ab type

Primary antibody

Background

NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of the gene, RELA. Four transcript variants encoding different isoforms have been found for RELA.

Reactivity

Human;Mouse;Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthetic Peptide of NF-κB p65

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

60219

synonyms

v-rel reticuloendotheliosis viral oncogene homolog A (avian)