Cloud-clone
SKU:MAA971Hu22
Monoclonal Antibody to Glypican 3 (GPC3)
Monoclonal Antibody to Glypican 3 (GPC3)
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;Immunohistochemistry: 5-20µg/mL
;Immunocytochemistry: 5-20µg/mL
;Optimal working dilutions must be determined by end user.
Product No.
MAA971Hu22
Organism Species
Homo sapiens (Human).
Source
Monoclonal antibody preparation
Host
Mouse
Potency (Clone Number)
C2
Ig Isotype
IgG2b Kappa
Purification
Protein A + Protein G affinity chromatography
Label
None
Immunogen
RPA971Hu01-Recombinant Glypican 3 (GPC3)
Buffer Formulation
PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Traits
Liquid
Concentration
1mg/mL
Organism Species More
Sus scrofa; Porcine (Pig)
Applications
WB; IHC; ICC; IP.
If the antibody is used in flow cytometry, please check FCM antibodies.
UOM
20µl 100µl 200µl 1ml 10ml
SPECIFITY
The antibody is a mouse monoclonal antibody raised against GPC3. It has been selected for its ability to recognize GPC3 in immunohistochemical staining and western blotting.
USAGE
Western blotting: 0.5-2µg/mL
Immunohistochemistry: 5-20µg/mL
Immunocytochemistry: 5-20µg/mL
Optimal working dilutions must be determined by end user.
STORAGE
Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
STABILITY
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
| Magazine | Citations |
| Nature and Science | Diagnostic Role of Serum Glypican-3 as a Tumor Marker for Hepatocellular Carcinoma Sciencepub:10043238 |
| Journal of Applied Pharmaceutical Science | Cytotoxic effects of antiglypican-3 against HepG2 cell line Ebscohost: Source |
| Asian Pacific Journal of Cancer Prevention | Can Glypican3 be Diagnostic for Early Hepatocellular Carcinoma among Egyptian Patients? Pubmed: 24460300 |
| Clin Biochem. | Diagnostic accuracy of serum glypican-3 for hepatocellular carcinoma: A systematic review and meta-analysis Pubmed: 24362268 |
| Science and Nature | Diagnostic Role of Serum Glypican-3 as Hepatocellular Carcinoma Zolcat: Source |
| Alexandria Journal of Medicine | Role of serum glypican-3 in the diagnosis and differentiation of small hepatocellular carcinoma from hepatitis-C virus cirrhosis ScienceDirect: S2090506814000062 |
| J Egypt Natl Canc Inst. | Comparing prothrombin induced by vitamin K absence-II (PIVKA-II) with the oncofetal proteins glypican-3, Alpha feto protein and carcinoembryonic antigen in diagnosing hepatocellular carcinoma among Egyptian patients. Pubmed:24841158 |
| European Journal of Pharmacology | Evaluation of antiglypican-3 therapy as a promising target for amelioration of hepatic tissue damage in hepatocellular carcinoma Pubmed:25449037 |
| Hepatobiliary Pancreat Dis Int | Predictive value of tumor markers in patients with recurrent hepatocellular carcinoma in different vascular invasion pattern abstract:abstract4525.shtml |
| Clinical and Molecular Hepatology | Glypican-3 level assessed by the enzyme-linked immunosorbent assay is inferior to alpha-fetoprotein level for hepatocellular carcinoma diagnosis pmc:articles |
| Wiley | Glypican‐3: A promising biomarker for hepatocellular carcinoma diagnosis and treatment pubmed:28621802 |
| Biomedicine & Pharmacotherapy | Cytotoxic and partial hepatoprotective activity of sodium ascorbate against hepatocellular carcinoma through inhibition of sulfatase-2 and Pubmed:29669302 |
| Journal of Cancer and Clinical Oncology | Development and Validation of a Two-Site Immunoradiometric assay for Glypican-3 in plasma: Implication in Diagnosis of Hepatocellular Carcinoma Researchgate:Source |
| Turkish journal of oncology | Serum Glypican-3, Vascular Endothelial Growth Factor, and Interleukin-6 Levels in Hepatocellular Carcinoma 10.5505:tjo.2018.1742 |
| Intensive Care Medicine Experimental | Elevated plasma glypicans are associated with organ failure in patients with infection Pubmed: 30618011 |
| VALUE OF SERUM GLYPICAN 3 AS A PREDICTIVE TOOL FOR EARLY DIAGNOSIS OF HEPATOCELLULAR CARCINOMA (HCC) | |
| ADVANCED RESEARCHES | Search for Effective Serum Tumor Markers for Early Diagnosis of Hepatocellular Carcinoma Associated with Hepatitis C |
| Life Sci | Selenium nanoparticles overcomes sorafenib resistance in thioacetamide induced hepatocellular carcinoma in rats by modulation of mTOR, NF-κB pathways and … Pubmed:35640776 |
| Catalog No. | Related products for research use of Homo sapiens (Human) Organism species | Applications (RESEARCH USE ONLY!) |
| RPA971Hu02 | Recombinant Glypican 3 (GPC3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPA971Hu01 | Recombinant Glypican 3 (GPC3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAA971Hu01 | Polyclonal Antibody to Glypican 3 (GPC3) | WB; ICC; IHC-P; IHC-F; ELISA. |
| MAA971Hu21 | Monoclonal Antibody to Glypican 3 (GPC3) | WB; IHC; ICC; IP. |
| MAA971Hu22 | Monoclonal Antibody to Glypican 3 (GPC3) | WB; IHC; ICC; IP. |
| MAA971Hu24 | Monoclonal Antibody to Glypican 3 (GPC3) | WB; IHC; ICC; IP. |
| MAA971Hu23 | Monoclonal Antibody to Glypican 3 (GPC3) | WB; IHC; ICC; IP. |
| MAA971Hu25 | Monoclonal Antibody to Glypican 3 (GPC3) | WB; IHC; ICC; IP. |
| SEA971Hu | ELISA Kit for Glypican 3 (GPC3) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| LMA971Hu | Magnetic Luminex Assay Kit for Glypican 3 (GPC3) ,etc. | Magnetic Luminex Assay for Antigen Detection. |
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