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SKU:MAB859Hu22

Monoclonal Antibody to Lectin Like Oxidized Low Density Lipoprotein Receptor 1 (LOX1)

Monoclonal Antibody to Lectin Like Oxidized Low Density Lipoprotein Receptor 1 (LOX1)

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UOM
Concentration
Organism species
Western blotting: 0.2-2µg/mL;1:500-5000
Immunohistochemistry: 5-20µg/mL;1:50-200
Immunocytochemistry: 5-20µg/mL;1:50-200
Optimal working dilutions must be determined by end user.

Product No.

MAB859Hu22

Organism Species

Homo sapiens (Human)

Source

Monoclonal antibody preparation

Host

Mouse

Potency (Clone Number)

C9

Ig Isotype

IgG1 Kappa

Purification

Protein A + Protein G affinity chromatography

Label

None

Immunogen

RPB859Hu01-Recombinant Lectin Like Oxidized Low Density Lipoprotein Receptor 1 (LOX1)

Buffer Formulation

0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.

Traits

Liquid

Concentration

1mg/mL

Organism Species More

n/a

Applications

WB; IHC; ICC; IP.

If the antibody is used in flow cytometry, please check FCM antibodies.

UOM

20µl 100µl 200µl 1ml 10ml



SPECIFITY

The antibody is a mouse monoclonal antibody raised against LOX1. It has been selected for its ability to recognize LOX1 in immunohistochemical staining and western blotting.

USAGE

Western blotting: 0.5-2µg/mL
Immunohistochemistry: 5-20µg/mL
Immunocytochemistry: 5-20µg/mL
Optimal working dilutions must be determined by end user.

STORAGE

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Magazine Citations
Clinical Cardiology Circulating Soluble Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 Levels Are Associated With Angiographic Coronary Lesion Complexity in Patients With Coronary Artery Diseas PubMed: 21400544
Coronary Artery Disease Postprocedural serum sLOX-1 levels are associated with coronary in-stent restenosis in patients with stable coronary artery disease LWW: 06000
Clinical Biochemistry Soluble lectin-like oxidized low-density lipoprotein receptor-1 levels in synovial fluid are correlated with disease severity of knee osteoarthritis ScienceDirect: S0009912011004905
Mediators of Inflammation Pregnancy Followed by Delivery May Affect Circulating Soluble Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 Levels in Women of Reproductive Age PubMed: 22619487
Dicle Medical Journal Lectin-like oxidized low density lipoprotein receptor 1(LOX-1) levels and endothelial dysfunction in patients with primary essential hyperhidrosis/Primer esansiyel hiperhidroz hastalarinda lektin benzeri okside düsük dansiteli lipoprotein reseptor 1(LOX-1) düzeyleri ve endotel disfonksiyonu Readperiodicals: Source
Journal of Clinical Laboratory Analysis Soluble Lectin-Like Oxidized LDL Receptor 1 as a Possible Mediator of Endothelial Dysfunction in Patients With Metabolic Syndrome Pubmed:24798146
Journal of Human Hypertension Endothelial damage in white coat hypertension: role of lectin-like oxidized low-density lipoprotein-1 Pubmed:25007999
Gynecologic and Obstetric Investigation Inhibition of Lectin-Like Oxidized Low-Density Lipoprotein Receptor 1 Protects against Plasma/Hypoxia-Mediated Trophoblast Dysfunction Associated with Preeclampsia Pubmed:25633310
World J Gastroenterol Increased serum soluble lectin-like oxidized low-density lipoprotein receptor-1 levels in patients with biopsy-proven nonalcoholic fatty liver disease PubMed: 26185381
Genetic Testing and Molecular Biomarkers Serum sLOX-1 Levels Are Correlated with the Presence and Severity of Obstructive Sleep Apnea PubMed: 25825846
Neurotoxicology. 27-Hydroxycholesterol regulates cholesterol synthesis and transport in C6 glioma cells. pubmed:28167099
Journal of the American Heart Association Increased Levels of Lectin‐Like Oxidized Low‐Density Lipoprotein Receptor‐1 in Ischemic Stroke and Transient Ischemic Attack Pubmed:29330254
Higher serum lectin-like oxidized low-density lipoprotein receptor-1 in patients with stable coronary artery disease is associated with major adverse …
Disease Markers Baseline Serum sLOX-1 Concentrations Are Associated with 2-Year Major Adverse Cardiovascular and Cerebrovascular Events in Patients after Percutaneous … Pubmed: 31772687
Reproductive Biology Polycystic ovary syndrome and endothelial dysfunction: A potential role for soluble lectin-like oxidized low density lipoprotein receptor-1 Pubmed: 32409108
Int J Cancer The oxidized‐LDL/LOX‐1 axis in tumor endothelial cells enhances metastasis by recruiting neutrophils and cancer cells Pubmed:35608341
Catalog No. Related products for research use of Homo sapiens (Human) Organism species Applications (RESEARCH USE ONLY!)
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