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SKU:PAB866Hu01
Polyclonal Antibody to Neuregulin 1 (NRG1)
Polyclonal Antibody to Neuregulin 1 (NRG1)
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Immunohistochemistry: 5-20µg/mL;1:50-200
Immunocytochemistry: 5-20µg/mL;1:50-200
Optimal working dilutions must be determined by end user.
Product No.
PAB866Hu01
Organism Species
Homo sapiens (Human)
Source
Polyclonal antibody preparation
Host
Rabbit
Potency
n/a
Ig Type
IgG
Purification
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Label
None
Immunogen
RPB866Hu01-Recombinant Neuregulin 1 (NRG1)
Buffer Formulation
0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Traits
Liquid
Concentration
1mg/ml
Organism Species More
Mus musculus (Mouse), Rattus norvegicus (Rat)
Applications
WB; IHC; ICC; IP.
If the antibody is used in flow cytometry, please check FCM antibodies.
UOM
20µl 100µl 200µl 1ml 10ml
SPECIFITY
The antibody is a rabbit polyclonal antibody raised against NRG1. It has been selected for its ability to recognize NRG1 in immunohistochemical staining and western blotting.
USAGE
Western blotting: 0.5-2µg/mL
Immunohistochemistry: 5-20µg/mL
Immunocytochemistry: 5-20µg/mL
Optimal working dilutions must be determined by end user.
STORAGE
Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
STABILITY
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
| Magazine | Citations |
| Neuroscience Letter | Therapeutic effect of co-transplantation of neuregulin 1-transfected-Schwann cells and bone marrow stromal cells on spinal cord hemisection syndrom Cyagen: source |
| PLoS One. | ADAM17 Silencing in Mouse Colon Carcinoma Cells: The Effect on Tumoricidal Cytokines and Angiogenesis PubMed: PMC3519469 |
| The Journal of Clinical Investigation | Cerebrospinal fluid–based kinetic biomarkers of axonal transport in monitoring neurodegeneration PubMed: PMC3428100 |
| Physiol Behav | Dysregulation of Neuregulin-1/ErbB signaling in the prefrontal cortex and hippocampus of rats exposed to chronic unpredictable mild stress PubMed: 26626816 |
| J Toxicol Sci. | Effects of prolonged antipsychotic administration on neureCavia (Guinea pig )lin-1/ErbB signaling in rat prefrontal cortex and myocardium: implications for the therapeutic action and cardiac adverse effect. Pubmed:26961615 |
| journal of cellular and molecular medicine | Qiliqiangxin protects against anoxic injury in cardiac microvascular endothelial cells via NRG-1/ErbB-PI3K/Akt/mTOR pathway. pubmed:28271613 |
| Transl Psychiatry. | Ablation of neuropsin-neuregulin 1 signaling imbalances ErbB4 inhibitory networks and disrupts hippocampal gamma oscillation. pubmed:28267150 |
| Human Molecular Genetics | A proteasome-resistant fragment of NIK mediates oncogenic NF-κB signaling in schwannomas Pubmed: 30335132 |
| Aging (Albany NY) | Jinmaitong ameliorates diabetic peripheral neuropathy in streptozotocin-induced diabetic rats by modulating gut microbiota and neuregulin Pubmed: 32920546 |
| Catalog No. | Related products for research use of Homo sapiens (Human) Organism species | Applications (RESEARCH USE ONLY!) |
| APB866Hu01 | Active Neuregulin 1 (NRG1) | Cell culture; Activity Assays. |
| RPB866Hu01 | Recombinant Neuregulin 1 (NRG1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAB866Hu01 | Polyclonal Antibody to Neuregulin 1 (NRG1) | WB; IHC; ICC; IP. |
| LAB866Hu71 | Biotin-Linked Polyclonal Antibody to Neuregulin 1 (NRG1) | WB; IHC; ICC. |
| MAB866Hu25 | Monoclonal Antibody to Neuregulin 1 (NRG1) | WB |
| MAB866Hu22 | Monoclonal Antibody to Neuregulin 1 (NRG1) | WB |
| MAB866Hu21 | Monoclonal Antibody to Neuregulin 1 (NRG1) | WB; IHC; ICC; IP. |
| MAB866Hu23 | Monoclonal Antibody to Neuregulin 1 (NRG1) | WB; IHC; ICC; IP. |
| MAB866Hu24 | Monoclonal Antibody to Neuregulin 1 (NRG1) | WB; IHC; ICC; IP. |
| SEB866Hu | ELISA Kit for Neuregulin 1 (NRG1) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| LMB866Hu | Magnetic Luminex Assay Kit for Neuregulin 1 (NRG1) ,etc. | Magnetic Luminex Assay for Antigen Detection. |
| KSB866Hu01 | ELISA Kit DIY Materials for Neuregulin 1 (NRG1) | Main materials for "Do It(ELISA Kit) Yourself" |
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