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SKU:PAB895Hu01

Polyclonal Antibody to Mannose Associated Serine Protease 1 (MASP1)

Polyclonal Antibody to Mannose Associated Serine Protease 1 (MASP1)

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UOM
Concentration
Organism species
Western blotting: 0.5-2µg/mL;
;Immunohistochemistry: 5-20µg/mL;
;Immunocytochemistry: 5-20µg/mL;
;Optimal working dilutions must be determined by end user.

Product No.

PAB895Hu01

Organism Species

Homo sapiens (Human) 

Source

Polyclonal antibody preparation

Host

Rabbit

Potency

n/a

Ig Type

IgG

Purification

Antigen-specific affinity chromatography followed by Protein A affinity chromatography

Label

None

Immunogen

RPB895Hu01-Recombinant Mannose Associated Serine Protease 1 (MASP1)

Buffer Formulation

0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.

Traits

Liquid

Concentration

500µg/mL

Organism Species More

Mus musculus (Mouse)

Applications

WB,IHC

If the antibody is used in flow cytometry, please check FCM antibodies.

UOM

20µl 100µl 200µl 1ml 10ml




SPECIFITY

The antibody is a rabbit polyclonal antibody raised against MASP1. It has been selected for its ability to recognize MASP1 in immunohistochemical staining and western blotting.

USAGE

Western blotting: 0.5-3µg/mL;
Immunohistochemistry: 5-20µg/mL;
Immunocytochemistry: 5-20µg/mL;
Optimal working dilutions must be determined by end user.

STORAGE

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Magazine Citations
Pathology Increased Circulating Plasma Mannose Binding Lectin Associated Serine Protease (Masp) As A Result of Enu-Induced Mutation in Masp-1 Lww: Source
The Journal fo Biological Chemistry Bisretinoid-mediated Complement Activation on Retinal Pigment Epithelial Cells Is Dependent on Complement Factor H Haplotype Pubmed:24550392
the journal of immunology The Levels of the Lectin Pathway Serine Protease MASP-1 and Its Complex Formation with C1 Inhibitor Are Linked to the Severity of Hereditary Angioedema PubMed: 26371246
J Neuroinflammation.  Mannose-binding lectin-associated serine protease 2 (MASP-2) contributes to poor disease outcome in humans and mice with pneumococcal meningitis PMC5234106
Frontiers in Immunology AmpliSeq screening of genes encoding the C-type lectin receptors and their signaling components reveals a common variant in MASP1 associated with … Pubmed:29515573
Journal of Proteomics Plasma proteome profiling of high-altitude polycythemia using TMT-based quantitative proteomics approach Pubmed: 30605725
Kidney International Reports Clinical value of complement activation biomarkers in overt diabetic nephropathy
Kidney International Reports Comparison of Complement Pathway Activation in Autoimmune Glomerulonephritis Pubmed:35571000
Catalog No. Related products for research use of Homo sapiens (Human) Organism species Applications (RESEARCH USE ONLY!)
RPB895Hu01 Recombinant Mannose Associated Serine Protease 1 (MASP1) Positive Control; Immunogen; SDS-PAGE; WB.
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SEB895Hu ELISA Kit for Mannose Associated Serine Protease 1 (MASP1) Enzyme-linked immunosorbent assay for Antigen Detection.
LMB895Hu Magnetic Luminex Assay Kit for Mannose Associated Serine Protease 1 (MASP1) ,etc. Magnetic Luminex Assay for Antigen Detection.

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