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SKU:MAB897Hu22
Monoclonal Antibody to Insulin Degrading Enzyme (IDE)
Monoclonal Antibody to Insulin Degrading Enzyme (IDE)
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Immunohistochemistry: 5-20µg/mL;1:50-200
Immunocytochemistry: 5-20µg/mL;1:50-200
Optimal working dilutions must be determined by end user.
Product No.
MAB897Hu22
Organism Species
Homo sapiens (Human).
Source
Monoclonal antibody preparation
Host
Mouse
Potency (Clone Number)
C2
Ig Isotype
IgG1 Kappa
Purification
Protein A + Protein G affinity chromatography
Label
None
Immunogen
RPB897Hu01-Recombinant Insulin Degrading Enzyme (IDE)
Buffer Formulation
0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Traits
Liquid
Concentration
0.8mg/ml
Organism Species More
n/a
Applications
WB; IHC; ICC; IP.
If the antibody is used in flow cytometry, please check FCM antibodies.
UOM
20µl 100µl 200µl 1ml 10ml
SPECIFITY
The antibody is a mouse monoclonal antibody raised against IDE. It has been selected for its ability to recognize IDE in immunohistochemical staining and western blotting.
USAGE
Western blotting: 0.01-2µg/mL;
Immunohistochemistry: 5-20µg/mL;
Immunofluorescence:5-20µg/mL;
Optimal working dilutions must be determined by end user.
STORAGE
Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
STABILITY
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
| Magazine | Citations |
| J Neurochem | Reduction PubMed: 26442993 |
| African Journal of Pharmacy and Pharmacology | Peptide hydroxamate derivatives as regulators for insulin receptor signaling and its degradation by zinc metalloprotease in diabetic rats article-full-text-pdf |
| Biomedicine & Pharmacotherapy | Vitamin D3 intake as regulator of insulin degrading enzyme and insulin receptor phosphorylationin diabetic rats. pubmed:27930980 |
| Biological Trace Element Research | Nigella sativa Oil and Chromium Picolinate Ameliorate Fructose-Induced Hyperinsulinemia by Enhancing Insulin Signaling and Suppressing Insulin-Degrading Enzyme in Male Rats 10.1007/s12011-017-1167-z |
| Neuroscience | The Protective Effects of IGF-I against β-Amyloid-related Downregulation of Hippocampal Somatostatinergic System Involve Activation of Akt and Protein Kinase A Pubmed:29406271 |
| Catalog No. | Related products for research use of Homo sapiens (Human) Organism species | Applications (RESEARCH USE ONLY!) |
| RPB897Hu01 | Recombinant Insulin Degrading Enzyme (IDE) | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAB897Hu01 | Polyclonal Antibody to Insulin Degrading Enzyme (IDE) | WB,IHC |
| MAB897Hu21 | Monoclonal Antibody to Insulin Degrading Enzyme (IDE) | WB; IHC; ICC; IP. |
| MAB897Hu22 | Monoclonal Antibody to Insulin Degrading Enzyme (IDE) | WB; IHC; ICC; IP. |
| SEB897Hu | ELISA Kit for Insulin Degrading Enzyme (IDE) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| LMB897Hu | Magnetic Luminex Assay Kit for Insulin Degrading Enzyme (IDE) ,etc. | Magnetic Luminex Assay for Antigen Detection. |
| KSB897Hu01 | ELISA Kit DIY Materials for Insulin Degrading Enzyme (IDE) | Main materials for "Do It(ELISA Kit) Yourself" |
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