Cloud-clone
SKU:PAB945Hu01
Polyclonal Antibody to Epiregulin (EREG)
Polyclonal Antibody to Epiregulin (EREG)
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;Immunohistochemistry: 5-20µg/mL;
;Immunocytochemistry: 5-20µg/mL;
;Optimal working dilutions must be determined by end user.
Product No.
PAB945Hu01
Organism Species
Homo sapiens (Human).
Source
Polyclonal antibody preparation
Host
Rabbit
Potency
n/a
Ig Type
IgG
Purification
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Label
None
Immunogen
RPB945Hu01-Recombinant Epiregulin (EREG)
Buffer Formulation
0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Traits
Liquid
Concentration
0.5mg/ml
Organism Species More
Sus scrofa; Porcine (Pig)
Applications
WB
If the antibody is used in flow cytometry, please check FCM antibodies.
UOM
20µl 100µl 200µl 1ml 10ml
SPECIFITY
The antibody is a rabbit polyclonal antibody raised against EREG. It has been selected for its ability to recognize EREG in immunohistochemical staining and western blotting.
USAGE
Western blotting: 0.01-2µg/mL;
Immunohistochemistry: 5-20µg/mL;
Immunocytochemistry: 5-20µg/mL;
Optimal working dilutions must be determined by end user.
STORAGE
Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
STABILITY
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
| Magazine | Citations |
| British Journal of Cancer | Cross-suppression of EGFR ligands amphiregulin and epiregulin and de-repression of FGFR3 signalling contribute to cetuximab resistance in wild-type KRAS tumour cells Nature: 2012103 |
| J Pharmacol Exp Ther. | Aryl hydrocarbon receptor antagonism attenuates growth factor expression, proliferation, and migration in fibroblast-like synoviocytes from patients with rheumatoid arthritis. Pubmed: 24309559 |
| Molecular Carcinogenesis | The Ah receptor regulates growth factor expression in head and neck squamous cell carcinoma cell lines Pubmed:23625689 |
| Am J Physiol Gastrointest Liver Physiol. | Epiregulin promotes the emergence and proliferation of adult liver progenitor cells. Pubmed:24812054 |
| European Review for Medical and Pharmacological Sciences | Epiregulin-loaded PLGA nanoparticles increase human keratinocytes proliferation: preliminary data pubmed:27383296 |
| Oncotarget | Overexpression of a functional calcium-sensing receptor dramatically increases osteolytic potential of MDA-MB-231 cells in a mouse model of bone metastasis through epiregulin-mediated osteoprotegerin downregulation PMC5593575 |
| American journal of respiratory cell and molecular biology | Potential Involvement of the Epidermal Growth Factor Receptor Ligand Epiregulin and Matrix Metalloproteinase-1 in Pathogenesis of Chronic Rhinosinusitis pubmed:28398769 |
| International Journal of Cancer | Epigenetic regulation of Amphiregulin and Epiregulin in colorectal cancer Pubmed: 30252132 |
| Epiregulin is released from intervertebral disks and induces spontaneous activity in pain pathways Doi: 10.1097/PR9.0000000000000718 | |
| Cell proliferation | Epiregulin enhances odontoblastic differentiation of dental pulp stem cells via activating MAPK signalling pathway Pubmed: 31454111 |
| International Journal of Molecular Sciences | Promising Therapeutic Efficacy of GC1118, an Anti-EGFR Antibody, against KRAS Mutation-Driven Colorectal Cancer Patient-Derived Xenografts Pubmed: 31771279 |
| Neoplasia | Patient-derived xenograft (PDX) models of colorectal carcinoma (CRC) as a platform for chemosensitivity and biomarker analysis in personalized medicine Pubmed: 33212364 |
| Reprod Sci | Compromised Cumulus-Oocyte Complex Matrix Organization and Expansion in Women with PCOS 34748173 |
| Tissue and Cell | MiR-192-5p suppresses M1 macrophage polarization via epiregulin (EREG) downregulation in gouty arthritis 34715618 |
| Catalog No. | Related products for research use of Homo sapiens (Human) Organism species | Applications (RESEARCH USE ONLY!) |
| RPB945Hu02 | Recombinant Epiregulin (EREG) | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPB945Hu04 | Recombinant Epiregulin (EREG) | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPB945Hu01 | Recombinant Epiregulin (EREG) | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPB945Hu03 | Recombinant Epiregulin (EREG) | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAB945Hu02 | Polyclonal Antibody to Epiregulin (EREG) | WB |
| PAB945Hu01 | Polyclonal Antibody to Epiregulin (EREG) | WB |
| PAB945Hu04 | Polyclonal Antibody to Epiregulin (EREG) | WB; IHC; ICC; IP. |
| MAB945Hu22 | Monoclonal Antibody to Epiregulin (EREG) | WB; IHC; ICC; IP. |
| SEB945Hu | ELISA Kit for Epiregulin (EREG) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| SCB945Hu | CLIA Kit for Epiregulin (EREG) | Chemiluminescent immunoassay for Antigen Detection. |
| LMB945Hu | Magnetic Luminex Assay Kit for Epiregulin (EREG) ,etc. | Magnetic Luminex Assay for Antigen Detection. |
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