Cloud-clone
SKU:MAB966Hu22
Monoclonal Antibody to Syndecan 1 (SDC1)
Monoclonal Antibody to Syndecan 1 (SDC1)
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;Immunohistochemistry: 5-20µg/mL;
;Immunocytochemistry: 5-20µg/mL;
;Optimal working dilutions must be determined by end user.
Product No.
MAB966Hu22
Organism Species
Homo sapiens (Human)
Source
Monoclonal antibody preparation
Host
Mouse
Potency (Clone Number)
C3
Ig Isotype
IgG1 Kappa
Purification
Protein A + Protein G affinity chromatography
Label
None
Immunogen
RPB966Hu01-Recombinant Syndecan 1 (SDC1)
Buffer Formulation
0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Traits
Liquid
Concentration
1mg/ml
Organism Species More
n/a
Applications
WB
If the antibody is used in flow cytometry, please check FCM antibodies.
UOM
20µl 100µl 200µl 1ml 10ml
SPECIFITY
The antibody is a mouse monoclonal antibody raised against SDC1. It has been selected for its ability to recognize SDC1 in immunohistochemical staining and western blotting.
USAGE
Western blotting: 0.01-2µg/mL;
Optimal working dilutions must be determined by end user.
STORAGE
Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
STABILITY
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
| Magazine | Citations |
| Molecular and Cellular Biochemistry | Increased level of soluble syndecan-1 in serum correlates with myocardial expression in a rat model of myocardial infarction SpringerLink: a201w3l18k257462 |
| Inflammation | Sdc1 Overexpression Inhibits the p38 MAPK Pathway and Lessens Fibrotic Ventricular Remodeling in MI Rats Springer: Source |
| Atherosclerosis. | Damage of the endothelial glycocalyx in chronic kidney disease Pubmed:24727235 |
| Journal of Trauma and Acute Care Surgery | Effect of valproic acid and injury on lesion size and endothelial glycocalyx shedding in a rodent model of isolated traumatic brain injury Pubmed:25058256 |
| Shock | Impairment of the Endothelial Glycocalyx in Cardiogenic Shock and its Prognostic Relevance Pubmed:25692257 |
| Mediators Inflamm | Dexamethasone Suppressed LPS-Induced Matrix Metalloproteinase and Its Effect on Endothelial Glycocalyx Shedding PubMed: 26199464 |
| Transplantation | Platelet-Derived Growth Factor-B Protects Rat Cardiac Allografts From Ischemia-reperfusion Injury. PubMed: 26371596 |
| Clinical and Experimental Nephrology | Dual antiplatelet and anticoagulant APAC prevents experimental ischemia–reperfusion-induced acute kidney injury pubmed:27405618 |
| Biomarkers in Medicine | Endothelial glycocalyx layer shedding following lung resection pubmed:27643669 |
| Danish National RESEARCH DATABASE | Resuscitation with Pooled and Pathogen-Reduced Plasma Attenuates the Increase in Brain Water Content following Traumatic Brain Injury and Hemorrhagic Shock in Rats 10.1089 |
| Journal of Neurotrauma | Resuscitation with pooled and pathogen-reduced plasma attenuates the increase in brain water content following traumatic brain injury and hemorrhagic shock in rats the rat. doi/10.1089/neu.2016.4574 |
| British Journal of Anaesthesia | Volume kinetics of Ringer's lactate solution in acute inflammatory disease 10.1016:j.bja.2018.04.023 |
| Arteriosclerosis, Thrombosis, and Vascular Biology | MPO (myeloperoxidase) reduces endothelial glycocalyx thickness dependent on its cationic charge Pubmed:29903730 |
| Shock | Plasma resuscitation improved survival in a cecal ligation and puncture rat model of sepsis Pubmed:28591008 |
| Shock | Experimental models of endotheliopathy: impact of shock severity Pubmed:28697004 |
| Journal of Trauma and Acute Care Surgery | Effects of propranolol and clonidine on brain edema, blood-brain barrier permeability, and endothelial glycocalyx disruption after fluid percussion brain injury in the rat Pubmed:28930945 |
| The Endothelial Glycocalyx in the Peritoneal Microcirculation of Rats with Chronic Kidney Failure Exposed to Dialysis Solutions 173015_06.pdf | |
| Journal of Surgical Research | Plasma ameliorates endothelial dysfunction in burn injury Doi: 10.1016/j.jss.2018.08.027 |
| Journal of Anesthesia | Dexmedetomidine preserves the endothelial glycocalyx and improves survival in a rat heatstroke model Pubmed: 30374889 |
| Anaesthesia | Postoperative microcirculatory perfusion and endothelial glycocalyx shedding following cardiac surgery with cardiopulmonary bypass Pubmed: 30687934 |
| Journal of Cardiothoracic and Vascular Anesthesial | Microvascular alterations during cardiac surgery using a heparin or phosphorylcholine coated circuit Pubmed: 31787433 |
| Hepatobiliary & Pancreatic Diseases International | Increased syndecan-1 and glypican-3 predict poor perinatal outcome and treatment resistance in intrahepatic cholestasis: Syndecan-1, glypican-3 and ICP Pubmed: 31919038 |
| Heparin Binding Protein and Endothelial Glycocalyx Markers in Severe COVID-19–A Prospective Observational Cohort Study | |
| INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | Newly Developed Recombinant Antithrombin Protects the Endothelial Glycocalyx in an Endotoxin-Induced Rat Model of Sepsis 33375342 |
| Microvasc Res | Effect of liraglutide on microcirculation in rat model with absolute insulin deficiency 34119534 |
| J Gerontol A Biol Sci Med Sci | The effect of pre-operative methylprednisolone on postoperative delirium in elderly patients undergoing gastrointestinal surgery: a randomized, double-blind, placebo … 34423832 |
| Shock | Inhalation of 2% hydrogen improves survival rate and attenuates shedding of vascular endothelial glycocalyx in rats with heat stroke 34524269 |
| Exp Anim | Dexmedetomidine suppresses serum syndecan-1 elevation and improves survival in a rat hemorrhagic shock model Pubmed:35110424 |
| Journal of Emergency Medicine | Resuscitation of hemorrhagic shock using normal saline does not damage the glycocalyx in the immediate resuscitation phase |
| Catalog No. | Related products for research use of Homo sapiens (Human) Organism species | Applications (RESEARCH USE ONLY!) |
| RPB966Hu01 | Recombinant Syndecan 1 (SDC1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| EPB966Hu61 | Eukaryotic Syndecan 1 (SDC1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAB966Hu01 | Polyclonal Antibody to Syndecan 1 (SDC1) | WB; IHC |
| FAB966Hu01 | Anti-Syndecan 1 (SDC1) Polyclonal Antibody | Flow cytometry. |
| FAB966Hu41 | PE-Linked Anti-Syndecan 1 (SDC1) Polyclonal Antibody | Flow cytometry. |
| FAB966Hu51 | APC-Linked Anti-Syndecan 1 (SDC1) Polyclonal Antibody | Flow cytometry. |
| FAB966Hu81 | FITC-Linked Anti-Syndecan 1 (SDC1) Polyclonal Antibody | Flow cytometry. |
| MAB966Hu21 | Monoclonal Antibody to Syndecan 1 (SDC1) | WB; IHC |
| MAB966Hu23 | Monoclonal Antibody to Syndecan 1 (SDC1) | WB |
| MAB966Hu22 | Monoclonal Antibody to Syndecan 1 (SDC1) | WB |
| MAB966Hu24 | Monoclonal Antibody to Syndecan 1 (SDC1) | WB; IHC; ICC; IP. |
| MAB966Hu25 | Monoclonal Antibody to Syndecan 1 (SDC1) | WB |
| RAB966Hu21 | Recombinant Antibody to Syndecan 1 (SDC1) | WB; IF; ICC; IHC; IP; FCM. |
| MAB966Hu27 | Monoclonal Antibody to Syndecan 1 (SDC1) | WB; IHC; ICC; IP. |
| MAB966Hu29 | Monoclonal Antibody to Syndecan 1 (SDC1) | WB; IHC; ICC; IP. |
| SEB966Hu | ELISA Kit for Syndecan 1 (SDC1) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| HEB966Hu | High Sensitive ELISA Kit for Syndecan 1 (SDC1) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| LMB966Hu | Magnetic Luminex Assay Kit for Syndecan 1 (SDC1) ,etc. | Magnetic Luminex Assay for Antigen Detection. |
| KSB966Hu01 | ELISA Kit DIY Materials for Syndecan 1 (SDC1) | Main materials for "Do It (ELISA Kit) Yourself". |
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