Cloud-clone
SKU:MAC128Hu22
Monoclonal Antibody to Gremlin 1 (GREM1)
Monoclonal Antibody to Gremlin 1 (GREM1)
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;Immunohistochemistry: 5-30µg/mL;
;Immunocytochemistry: 5-30µg/mL;
;Optimal working dilutions must be determined by end user.
Product No.
MAC128Hu22
Organism Species
Homo sapiens (Human)
Source
Monoclonal antibody preparation
Host
Mouse
Potency (Clone Number)
C1
Ig Isotype
IgG1 Kappa
Purification
Protein A + Protein G affinity chromatography
Label
None
Immunogen
RPC128Hu02-Recombinant Gremlin 1 (GREM1)
Buffer Formulation
0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Traits
Liquid
Concentration
1mg/ml
Organism Species More
n/a
Applications
WB,IHC
If the antibody is used in flow cytometry, please check FCM antibodies.
UOM
20µl 100µl 200µl 1ml 10ml
SPECIFITY
The antibody is a mouse monoclonal antibody raised against GREM1. It has been selected for its ability to recognize GREM1 in immunohistochemical staining and western blotting.
USAGE
Western blotting: 0.5-3µg/mL;
Immunohistochemistry: 5-30µg/mL;
Immunocytochemistry: 5-30µg/mL;
Optimal working dilutions must be determined by end user.
STORAGE
Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
STABILITY
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
| Magazine | Citations |
| Lung | Intrinsic BMP Antagonist Gremlin-1 as a Novel Circulating Marker in Pulmonary Arterial Hypertension PubMed: 25926293 |
| Tumour Biol | Overexpression of Gremlin promotes non-small cell lung cancer progression PubMed: 26392110 |
| Int J Cardiol | Triple head-to-head comparison of fibrotic biomarkers galectin-3, osteopontin and gremlin-1 for long-term prognosis in suspected and proven acute heart failure patients PubMed: 26539964 |
| International Journal of Cardiology | Triple head-to-head comparison of fibrotic biomarkers galectin-3, osteopontin and gremlin-1 for long-termprognosis in suspected and proven acute heart failure patients Pubmed:26539964 |
| American Journal of Respiratory Cell and Molecular Biology | BMPR2 Mutation-independent Mechanisms of Disrupted BMP Signaling in IPAH Pubmed:27187737 |
| J Rheumatol | GREM1 Is a Key ReCavia (Guinea pig )lator of Synoviocyte Hyperplasia and Invasiveness Pubmed:26834210 |
| European cells & materials | The BMP2 variant L51P restores the osteogenic differentiation of human mesenchymal stromal cells in the presence of intervertebral disc cells. pubmed:28266688 |
| Sci Rep. | Genomic reprograming analysis of the Mesothelial to Mesenchymal Transition identifies biomarkers in peritoneal dialysis patients. pubmed:28327551 |
| American Journal of Respiratory Cell and Molecular Biology | Bone Morphogenic Protein Type 2 Receptor Mutation-Independent Mechanisms of Disrupted Bone Morphogenetic Protein Signaling in Idiopathic Pulmonary Arterial … rcmb.2015-0402OC |
| Molecular Medicine Reports | Gremlin-1 suppression increases BMP-2-induced osteogenesis of human mesenchymal stem cells pubmed:28260028 |
| Cellular Haemostasis and Platelets | Platelets as a novel source of Gremlin-1: Implications for thrombo inflammation pubmed:27929199 |
| Scientific Reports | Gremlin, A Potential Urinary Biomarker of Anca-Associated Crescentic Glomerulonephritis Pubmed: 31053735 |
| International Journal of Molecular Sciences | Transcriptomic and Proteomic Analyses Reveal the Potential Mode of Action of Chondrocyte Sheets in Hyaline Cartilage Regeneration Pubmed: 31878307 |
| American Journal of Physiology-Cell Physiology | Suppression of microRNA-23a/b-3p delays the development degenerative joint disease by activating Grem1 and TGF-β/Smad signaling pathway Pubmed: 32186934 |
| Inflammopharmacology | Protective role of microRNA-23a/b-3p inhibition against osteoarthritis through Gremlin1-depenent activation of TGF-β/smad signaling in chondrocytesa Pubmed:35441352 |
| Mol Carcinog | CAF‐derived exosomes transmitted Gremlin‐1 promotes cancer progression and decreases the sensitivity of hepatoma cells to sorafenib Pubmed:35638711 |
| Catalog No. | Related products for research use of Homo sapiens (Human) Organism species | Applications (RESEARCH USE ONLY!) |
| APC128Hu02 | Active Gremlin 1 (GREM1) | Cell culture; Activity Assays. |
| RPC128Hu01 | Recombinant Gremlin 1 (GREM1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| APC128Hu01 | Active Gremlin 1 (GREM1) | Cell culture; Activity Assays. |
| RPC128Hu02 | Recombinant Gremlin 1 (GREM1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAC128Hu01 | Polyclonal Antibody to Gremlin 1 (GREM1) | WB; IHC; ICC; IP. |
| PAC128Hu02 | Polyclonal Antibody to Gremlin 1 (GREM1) | WB; IHC; ICC; IP. |
| LAC128Hu81 | FITC-Linked Polyclonal Antibody to Gremlin 1 (GREM1) | WB; IHC; ICC; IF. |
| LAC128Hu71 | Biotin-Linked Polyclonal Antibody to Gremlin 1 (GREM1) | WB; IHC; ICC. |
| MAC128Hu21 | Monoclonal Antibody to Gremlin 1 (GREM1) | WB; IHC; ICC; IP. |
| MAC128Hu23 | Monoclonal Antibody to Gremlin 1 (GREM1) | WB; IHC; ICC; IP. |
| RAC128Hu21 | Recombinant Antibody to Gremlin 1 (GREM1) | WB; IF; ICC; IHC; IP; FCM. |
| MAC128Hu22 | Monoclonal Antibody to Gremlin 1 (GREM1) | WB,IHC |
| SEC128Hu | ELISA Kit for Gremlin 1 (GREM1) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| LMC128Hu | Magnetic Luminex Assay Kit for Gremlin 1 (GREM1) ,etc. | Magnetic Luminex Assay for Antigen Detection. |
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