Cloud-clone
SKU:PAC128Mu01
Polyclonal Antibody to Gremlin 1 (GREM1)
Polyclonal Antibody to Gremlin 1 (GREM1)
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Immunohistochemistry: 5-20µg/mL;
Immunocytochemistry: 5-20µg/mL;
Optimal working dilutions must be determined by end user.
Product No.
PAC128Mu01
Organism Species
Mus musculus (Mouse)
Source
Polyclonal antibody preparation
Host
Rabbit
Potency
n/a
Ig Type
IgG
Purification
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Label
None
Immunogen
RPC128Mu01-Recombinant Gremlin 1 (GREM1)
Buffer Formulation
0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Traits
Liquid
Concentration
0.5mg/ml
Organism Species More
n/a
Applications
WB,IHC
If the antibody is used in flow cytometry, please check FCM antibodies.
UOM
20µl 100µl 200µl 1ml 10ml
SPECIFITY
The antibody is a rabbit polyclonal antibody raised against GREM1. It has been selected for its ability to recognize GREM1 in immunohistochemical staining and western blotting.
USAGE
Western blotting: 0.01-2µg/mL;
Immunohistochemistry: 5-20µg/mL;
Immunocytochemistry: 5-20µg/mL;
Optimal working dilutions must be determined by end user.
STORAGE
Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
STABILITY
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
| Magazine | Citations |
| Lung | Intrinsic BMP Antagonist Gremlin-1 as a Novel Circulating Marker in Pulmonary Arterial Hypertension PubMed: 25926293 |
| Tumour Biol | Overexpression of Gremlin promotes non-small cell lung cancer progression PubMed: 26392110 |
| Int J Cardiol | Triple head-to-head comparison of fibrotic biomarkers galectin-3, osteopontin and gremlin-1 for long-term prognosis in suspected and proven acute heart failure patients PubMed: 26539964 |
| International Journal of Cardiology | Triple head-to-head comparison of fibrotic biomarkers galectin-3, osteopontin and gremlin-1 for long-termprognosis in suspected and proven acute heart failure patients Pubmed:26539964 |
| American Journal of Respiratory Cell and Molecular Biology | BMPR2 Mutation-independent Mechanisms of Disrupted BMP Signaling in IPAH Pubmed:27187737 |
| J Rheumatol | GREM1 Is a Key ReCavia (Guinea pig )lator of Synoviocyte Hyperplasia and Invasiveness Pubmed:26834210 |
| European cells & materials | The BMP2 variant L51P restores the osteogenic differentiation of human mesenchymal stromal cells in the presence of intervertebral disc cells. pubmed:28266688 |
| Sci Rep. | Genomic reprograming analysis of the Mesothelial to Mesenchymal Transition identifies biomarkers in peritoneal dialysis patients. pubmed:28327551 |
| American Journal of Respiratory Cell and Molecular Biology | Bone Morphogenic Protein Type 2 Receptor Mutation-Independent Mechanisms of Disrupted Bone Morphogenetic Protein Signaling in Idiopathic Pulmonary Arterial … rcmb.2015-0402OC |
| Molecular Medicine Reports | Gremlin-1 suppression increases BMP-2-induced osteogenesis of human mesenchymal stem cells pubmed:28260028 |
| Cellular Haemostasis and Platelets | Platelets as a novel source of Gremlin-1: Implications for thrombo inflammation pubmed:27929199 |
| Scientific Reports | Gremlin, A Potential Urinary Biomarker of Anca-Associated Crescentic Glomerulonephritis Pubmed: 31053735 |
| International Journal of Molecular Sciences | Transcriptomic and Proteomic Analyses Reveal the Potential Mode of Action of Chondrocyte Sheets in Hyaline Cartilage Regeneration Pubmed: 31878307 |
| American Journal of Physiology-Cell Physiology | Suppression of microRNA-23a/b-3p delays the development degenerative joint disease by activating Grem1 and TGF-β/Smad signaling pathway Pubmed: 32186934 |
| Inflammopharmacology | Protective role of microRNA-23a/b-3p inhibition against osteoarthritis through Gremlin1-depenent activation of TGF-β/smad signaling in chondrocytesa Pubmed:35441352 |
| Mol Carcinog | CAF‐derived exosomes transmitted Gremlin‐1 promotes cancer progression and decreases the sensitivity of hepatoma cells to sorafenib Pubmed:35638711 |
| Catalog No. | Related products for research use of Mus musculus (Mouse) Organism species | Applications (RESEARCH USE ONLY!) |
| RPC128Mu01 | Recombinant Gremlin 1 (GREM1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPC128Mu02 | Recombinant Gremlin 1 (GREM1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| APC128Mu01 | Active Gremlin 1 (GREM1) | Cell culture; Activity Assays. |
| PAC128Mu01 | Polyclonal Antibody to Gremlin 1 (GREM1) | WB,IHC |
| PAC128Mu02 | Polyclonal Antibody to Gremlin 1 (GREM1) | WB; IHC; ICC; IP. |
| LAC128Mu81 | FITC-Linked Polyclonal Antibody to Gremlin 1 (GREM1) | WB; IHC; ICC; IF. |
| LAC128Mu71 | Biotin-Linked Polyclonal Antibody to Gremlin 1 (GREM1) | WB; IHC; ICC. |
| SEC128Mu | ELISA Kit for Gremlin 1 (GREM1) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| LMC128Mu | Magnetic Luminex Assay Kit for Gremlin 1 (GREM1) ,etc. | Magnetic Luminex Assay for Antigen Detection. |
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