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SKU:PAC268Hu01
Polyclonal Antibody to 11-Beta-Hydroxysteroid Dehydrogenase Type 1 (HSD11b1)
Polyclonal Antibody to 11-Beta-Hydroxysteroid Dehydrogenase Type 1 (HSD11b1)
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Immunohistochemistry: 5-20µg/mL;1:25-100
Immunocytochemistry: 5-20µg/mL;1:25-100
Optimal working dilutions must be determined by end user.
Product No.
PAC268Hu01
Organism Species
Homo sapiens (Human)
Source
Polyclonal antibody preparation
Host
Rabbit
Potency
n/a
Ig Type
IgG
Purification
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Label
None
Immunogen
n/a
Buffer Formulation
PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Traits
Liquid
Concentration
500µg/mL
Organism Species More
n/a
Applications
WB; IHC; ICC; IP.
If the antibody is used in flow cytometry, please check FCM antibodies.
UOM
20µl 100µl 200µl 1ml 10ml
SPECIFITY
The antibody is a rabbit polyclonal antibody raised against HSD11b1. It has been selected for its ability to recognize HSD11b1 in immunohistochemical staining and western blotting.
USAGE
Western blotting: 0.2-2µg/mL;1:250-2500
Immunohistochemistry: 5-20µg/mL;1:25-100
Immunocytochemistry: 5-20µg/mL;1:25-100
Optimal working dilutions must be determined by end user.
STORAGE
Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
STABILITY
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
| Magazine | Citations |
| Journal of Endocrinology | Uninephrectomy reduces 11β-hydroxysteroid dehydrogenase type 1 and type 2 concomitantly with an increase in blood pressure in rats PubMed: 22739210 |
| Evid Based Complement Alternat Med | Anti-Inflammatory Property of PubMed: 26300946 |
| Molecules | Piper sarmentosum Effects on 11β-Hydroxysteroid Dehydrogenase Type 1 Enzyme in Serumand Bone in Rat Model of Glucocorticoid-Induced Osteoporosis. pubmed:27854305 |
| Bioorganic Chemistry | A novel derivatives of thiazol-4 (5H)-one and their activity in the inhibition of 11β-hydroxysteroid dehydrogenase type 1 Pubmed:29738970 |
| Malaysian Journal of Medical Sciences | An Evidence-Based Review: The Effects of Malaysian Traditional Herbs on Osteoporotic Rat Models |
| 2.583 | Application of ELISA Technique and Human Microsomes in the Search for 11β-Hydroxysteroid Dehydrogenase Inhibitors Doi: BioMed Research International |
| Chemistry & Biodiversity | Synthesis of the N‐methyl derivatives of 2‐aminothiazol‐4 (5H)‐one and their interactions with 11βHSD1‐molecular modeling and in vitro studies Pubmed: 31012543 |
| Oxidative Medicine and Cellular Longevity | Hepatoprotective Effects of Morinda citrifolia Leaf Extract on Ovariectomized Rats Fed with Thermoxidized Palm Oil Diet: Evidence at Histological and Ultrastructural … Pubmed: 31827717 |
| Catalog No. | Related products for research use of Homo sapiens (Human) Organism species | Applications (RESEARCH USE ONLY!) |
| RPC268Hu01 | Recombinant 11-Beta-Hydroxysteroid Dehydrogenase Type 1 (HSD11b1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAC268Hu01 | Polyclonal Antibody to 11-Beta-Hydroxysteroid Dehydrogenase Type 1 (HSD11b1) | WB; IHC; ICC; IP. |
| MAC268Hu22 | Monoclonal Antibody to 11-Beta-Hydroxysteroid Dehydrogenase Type 1 (HSD11b1) | WB; IHC; ICC; IP. |
| SEC268Hu | ELISA Kit for 11-Beta-Hydroxysteroid Dehydrogenase Type 1 (HSD11b1) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| LMC268Hu | Magnetic Luminex Assay Kit for 11-Beta-Hydroxysteroid Dehydrogenase Type 1 (HSD11b1) ,etc. | Magnetic Luminex Assay for Antigen Detection. |
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